Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | STING1 | Q86WV6 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8401799 | 0.91 | SMN1; SMN2 (0.41) | ALDH1A1KDM4EL3MBTL1GAASMN1; SMN2 | |
| SCHEMBL8396110 | 0.90 | AKR1B1 (0.41) | ALDH1A1KDM4EHSD17B10TSHRGAA | |
| SCHEMBL8399112 | 0.90 | SMN1; SMN2 (0.40) | ALDH1A1KDM4ETSHRL3MBTL1GAA | |
| SCHEMBL8399175 | 0.88 | SMN1; SMN2 (0.39) | ALDH1A1KDM4EL3MBTL1GAASMN1; SMN2 | |
| SCHEMBL8395796 | 0.88 | SMN1; SMN2 (0.39) | ALDH1A1KDM4EL3MBTL1GAASMN1; SMN2 | |
| SCHEMBL8399080 | 0.87 | SMN1; SMN2 (0.38) | ALDH1A1KDM4EHSD17B10L3MBTL1GAA | |
| SCHEMBL8396328 | 0.87 | AKR1B1 (0.42) | ALDH1A1KDM4EHSD17B10TSHRL3MBTL1 | |
| SCHEMBL8399202 | 0.86 | SMN1; SMN2 (0.52) | ALDH1A1L3MBTL1GAASMN1; SMN2AKR1B1 | |
| SCHEMBL8399110 | 0.86 | ALDH1A1 (0.39) | ALDH1A1KDM4EHSD17B10TSHRL3MBTL1 | |
| SCHEMBL8400564 | 0.86 | ALDH1A1 (0.39) | ALDH1A1KDM4EHSD17B10TSHRL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0647636-B1 | BENZOTHIAZOLE COMPOUND, PROCESS FOR PRODUCING THE SAME, AND USE THEREOF | SENJU PHARMA CO (JP) | 1999-06-09 | — | — | EP | disclosed |
| US-5532257-A | ENZYME INHIBITOR | SENJU PHARMACEUTICAL CO., LTD (JP) | 1996-07-02 | — | — | US | disclosed |
| EP-0647636-A1 | BENZOTHIAZOLE COMPOUND, PROCESS FOR PRODUCING THE SAME, AND USE THEREOF | Senju Pharmaceutical Co., Ltd. (JP) | 1995-04-12 | — | — | EP | disclosed |