Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA3 | P22001 | 1/20 | 0.59 |
| ▸ | CA12 | O43570 | 1/20 | 0.57 |
| ▸ | CA1 | P00915 | 1/20 | 0.57 |
| ▸ | CA9 | Q16790 | 1/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.52 |
| ▸ | TNKS | O95271 | 1/20 | 0.52 |
| ▸ | PARP1 | P09874 | 1/20 | 0.52 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.52 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.52 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.52 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.52 |
| ▸ | PARP3 | Q9Y6F1 | 1/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14473803 | 0.87 | KCNA3 (0.63) | KCNA3CA12CA1CA9KDM4E | |
| SCHEMBL8871233 | 0.83 | ALOX15 (0.60) | KCNA3CA12CA1CA9ALOX15 | |
| SCHEMBL4262132 | 0.81 | MEN1 (0.64) | KCNA3CA12CA1CA9KDM4E | |
| SCHEMBL29468148 | 0.78 | KMT2A (0.68) | KCNA3CA12CA1CA9KDM4E | |
| SCHEMBL11452110 | 0.77 | KCNA3 (0.65) | KCNA3CA12CA1CA9MEN1 | |
| SCHEMBL6592785 | 0.77 | KCNA3 (0.69) | KCNA3CA12CA1CA9ALOX15 | |
| SCHEMBL15842782 | 0.76 | CYP2A6 (0.67) | KCNA3CA12CA1CA9KDM4E | |
| SCHEMBL6599915 | 0.75 | KCNA3 (0.72) | KCNA3CA12CA1CA9ALOX15 | |
| SCHEMBL7352567 | 0.75 | CA12 (0.53) | KCNA3CA12CA1CA9ALOX15 | |
| SCHEMBL6258749 | 0.75 | MIF (0.64) | CA12CA1CA9KDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5962460-A | CONTROLLING CANCER GROWTH | NATIONAL SCIENCE COUNCIL (TAIWAN) (TW) | 1999-10-05 | — | — | US | disclosed |
| US-5646164-A | FOR THE TREATMENT OR PREVENTION OF CARDIOVASCULAR DISEASE | NATIONAL SCIENCE COUNCIL (TW) | 1997-07-08 | — | — | US | disclosed |