Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IKBKB | O14920 | 4/20 | 0.33 |
| ▸ | RARA | P10276 | 2/20 | 0.33 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8572140 | 0.91 | RARA (0.38) | IKBKBRARAS1PR1 | |
| SCHEMBL8436371 | 0.85 | S1PR1 (0.34) | IKBKBRARAS1PR1 | |
| SCHEMBL8571679 | 0.83 | IKBKB (0.32) | IKBKBRARAS1PR1 | |
| SCHEMBL8398813 | 0.83 | MEN1 (0.36) | IKBKBRARA | |
| SCHEMBL8433273 | 0.82 | RARA (0.45) | IKBKBRARA | |
| SCHEMBL8397932 | 0.82 | IKBKB (0.48) | IKBKBRARAS1PR1 | |
| SCHEMBL8568927 | 0.81 | S1PR1 (0.34) | IKBKBRARAS1PR1 | |
| SCHEMBL8570456 | 0.80 | RARA (0.38) | IKBKBRARAS1PR1 | |
| SCHEMBL8394244 | 0.80 | RARA (0.38) | IKBKBRARA | |
| SCHEMBL8394318 | 0.79 | IKBKB (0.41) | IKBKBRARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0776881-B1 | Bi-aromatic compounds comprising an adamantyl group in para-position, pharmaceutical and cosmetic compositions containing them and their utilization | CIRD GALDERMA (FR) | 1999-12-08 | — | — | EP | disclosed |
| US-5877342-A | SKIN DISORDERS; RESPIRATORY SYSTEM DISORDERS; CARDIOVASCULAR DISORDERS | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUIES GALDERMA (FR) | 1999-03-02 | — | — | US | disclosed |
| EP-0776881-A1 | Bi-aromatic compounds comprising an adamantyl group in para-position, pharmaceutical and cosmetic compositions containing them and their utilization | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES GALDERMA (C.I.R.D. GALDERMA) (FR) | 1997-06-04 | — | — | EP | disclosed |