Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | LTB4R2 | Q9NPC1 | 6/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | POLQ | O75417 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.36 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8399172 | 0.92 | LTB4R2 (0.45) | SMN1; SMN2MAPTLTB4R2NPC1OPRM1 | |
| SCHEMBL8398029 | 0.89 | LTB4R2 (0.42) | SMN1; SMN2LTB4R2NPC1OPRM1KCNH2 | |
| SCHEMBL8396593 | 0.88 | SMN1; SMN2 (0.54) | SMN1; SMN2MAPTLTB4R2NPC1POLQ | |
| SCHEMBL8395141 | 0.86 | SMN1; SMN2 (0.52) | SMN1; SMN2MAPTPOLQLMNACYP4F2 | |
| SCHEMBL8399240 | 0.86 | SMN1; SMN2 (0.52) | SMN1; SMN2NPC1POLQCYP4F2CYP4A11 | |
| SCHEMBL8398292 | 0.86 | SMN1; SMN2 (0.52) | SMN1; SMN2MAPTLTB4R2NPC1 | |
| SCHEMBL8395306 | 0.85 | SMN1; SMN2 (0.53) | SMN1; SMN2MAPTLTB4R2LMNAL3MBTL1 | |
| SCHEMBL8398077 | 0.85 | SMN1; SMN2 (0.72) | SMN1; SMN2POLQCYP4F2CYP4A11 | |
| SCHEMBL8400239 | 0.85 | SMN1; SMN2 (0.51) | SMN1; SMN2MAPTNPC1 | |
| SCHEMBL8399194 | 0.85 | SMN1; SMN2 (0.51) | SMN1; SMN2MAPTNPC1LMNAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0647636-B1 | BENZOTHIAZOLE COMPOUND, PROCESS FOR PRODUCING THE SAME, AND USE THEREOF | SENJU PHARMA CO (JP) | 1999-06-09 | — | — | EP | disclosed |
| US-5532257-A | ENZYME INHIBITOR | SENJU PHARMACEUTICAL CO., LTD (JP) | 1996-07-02 | — | — | US | disclosed |
| EP-0647636-A1 | BENZOTHIAZOLE COMPOUND, PROCESS FOR PRODUCING THE SAME, AND USE THEREOF | Senju Pharmaceutical Co., Ltd. (JP) | 1995-04-12 | — | — | EP | disclosed |