Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R2 | Q9NPC1 | 6/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.37 |
| ▸ | POLQ | O75417 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8398241 | 0.92 | SMN1; SMN2 (0.52) | LTB4R2SMN1; SMN2MAPTOPRM1KCNH2 | |
| SCHEMBL8396315 | 0.88 | SMN1; SMN2 (0.47) | LTB4R2SMN1; SMN2MAPTPOLQNPC1 | |
| SCHEMBL8395385 | 0.87 | SMN1; SMN2 (0.43) | LTB4R2SMN1; SMN2MAPTSIGMAR1POLQ | |
| SCHEMBL8399265 | 0.87 | SMN1; SMN2 (0.47) | LTB4R2SMN1; SMN2MAPTNPC1KMT2A | |
| SCHEMBL8399213 | 0.87 | SMN1; SMN2 (0.43) | LTB4R2SMN1; SMN2MEN1KMT2ATP53 | |
| SCHEMBL8400205 | 0.87 | SMN1; SMN2 (0.43) | LTB4R2SMN1; SMN2MAPTPOLQMEN1 | |
| SCHEMBL8398029 | 0.86 | LTB4R2 (0.42) | LTB4R2SMN1; SMN2OPRM1KCNH2SIGMAR1 | |
| SCHEMBL8399169 | 0.86 | SMN1; SMN2 (0.44) | LTB4R2SMN1; SMN2MAPTL3MBTL1MEN1 | |
| SCHEMBL8396409 | 0.86 | SMN1; SMN2 (0.59) | LTB4R2SMN1; SMN2POLQNPC1MEN1 | |
| SCHEMBL8396177 | 0.86 | MTNR1A (0.45) | LTB4R2SMN1; SMN2MAPTL3MBTL1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0647636-B1 | BENZOTHIAZOLE COMPOUND, PROCESS FOR PRODUCING THE SAME, AND USE THEREOF | SENJU PHARMA CO (JP) | 1999-06-09 | — | — | EP | disclosed |
| US-5532257-A | ENZYME INHIBITOR | SENJU PHARMACEUTICAL CO., LTD (JP) | 1996-07-02 | — | — | US | disclosed |
| EP-0647636-A1 | BENZOTHIAZOLE COMPOUND, PROCESS FOR PRODUCING THE SAME, AND USE THEREOF | Senju Pharmaceutical Co., Ltd. (JP) | 1995-04-12 | — | — | EP | disclosed |