Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 5/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.35 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.32 |
| ▸ | F2 | P00734 | 1/20 | 0.32 |
| ▸ | PLG | P00747 | 1/20 | 0.32 |
| ▸ | PLAU | P00749 | 1/20 | 0.32 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.32 |
| ▸ | KLK1 | P06870 | 1/20 | 0.32 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8741217 | 0.88 | SIGMAR1 (0.44) | SIGMAR1ALOX5 | |
| SCHEMBL9626664 | 0.85 | SIGMAR1 (0.54) | SIGMAR1CYP1A2ALOX5 | |
| SCHEMBL9627587 | 0.81 | SIGMAR1 (0.42) | SIGMAR1CYP1A2ALOX5CYP3A4SLC6A2 | |
| SCHEMBL8332260 | 0.78 | HRH4 (0.36) | SIGMAR1RECQL | |
| SCHEMBL25763688 | 0.74 | CYP1A2 (0.48) | CYP1A2CYP2A6RECQLCYP3A4SLC6A2 | |
| SCHEMBL8741327 | 0.73 | SIGMAR1 (0.49) | SIGMAR1CYP2D6 | |
| SCHEMBL8334067 | 0.73 | SIGMAR1 (0.37) | SIGMAR1CYP1A2CYP3A4SLC6A2 | |
| SCHEMBL6158953 | 0.72 | SIGMAR1 (0.39) | SIGMAR1ALOX5 | |
| SCHEMBL6156768 | 0.72 | SIGMAR1 (0.40) | SIGMAR1ALOX5 | |
| SCHEMBL6720820 | 0.72 | RECQL (0.52) | SIGMAR1CYP1A2CYP2A6RECQLCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0918460-A1 | METHODS OF TREATMENT OF EYE TRAUMA AND DISORDERS | CAMBRIDGE NEUROSCIENCE, INC. (US) | 1999-06-02 | — | — | EP | disclosed |
| WO-1998004131-A1 | METHODS OF TREATMENT OF EYE TRAUMA AND DISORDERS | CAMBRIDGE NEUROSCIENCE, INC. (US) | 1998-02-05 | — | — | WO | disclosed |