Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.63 |
| ▸ | LMNA | P02545 | 1/20 | 0.63 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.57 |
| ▸ | HTT | P42858 | 3/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | USP2 | O75604 | 1/20 | 0.52 |
| ▸ | CASP1 | P29466 | 1/20 | 0.52 |
| ▸ | CASP7 | P55210 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.47 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.47 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.47 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.46 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3417306 | 0.83 | HTT (0.73) | ALDH1A1HTTPOLBFGFR1MKNK1 | |
| SCHEMBL7211152 | 0.82 | HTT (0.49) | HPGDALDH1A1LMNAHTTPOLB | |
| SCHEMBL7210786 | 0.82 | HTT (0.49) | HPGDALDH1A1LMNAHCAR1HTT | |
| SCHEMBL30026657 | 0.79 | PKM (0.53) | HPGDALDH1A1LMNAHTTKDM4E | |
| SCHEMBL12138417 | 0.79 | HTT (0.56) | HPGDHCAR1HTTKDM4EPOLB | |
| SCHEMBL29830215 | 0.79 | HTT (0.56) | HPGDHCAR1HTTKDM4EPOLB | |
| SCHEMBL541062 | 0.79 | HTT (0.45) | HPGDALDH1A1LMNAHTTPOLB | |
| SCHEMBL23266636 | 0.78 | HTT (0.60) | ALDH1A1HTTPOLBFGFR1MKNK1 | |
| SCHEMBL11793167 | 0.77 | MAPT (0.48) | HPGDALDH1A1LMNAHTTPOLB | |
| SCHEMBL23840256 | 0.77 | HTT (0.58) | ALDH1A1HTTPOLBFGFR1MKNK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100478031-C | The use of substituted tetracyclic imidazole derivatives as anti-histaminics | JANSSEN PHARMACEUTICA NV (BE) | 2009-04-15 | — | — | CN | disclosed |
| CN-1895673-A | The use of substituted tetracyclic imidazole derivatives as anti-histaminics | JANSSEN PHARMACEUTICA NV (BE) | 2007-01-17 | — | — | CN | disclosed |
| EP-0619333-B1 | Process for coating metals | ATOTECH DEUTSCHLAND GMBH (DE) | 1999-06-02 | — | — | EP | disclosed |
| EP-0794847-B1 | PROCESS FOR BONDING WIRES TO OXIDATION-SENSITIVE METAL SUBSTRATES WHICH CAN BE SOLDERED | ATOTECH DEUTSCHLAND GMBH (DE) | 1998-07-22 | — | — | EP | disclosed |
| EP-0794847-A1 | PROCESS FOR BONDING WIRES TO OXIDATION-SENSITIVE METAL SUBSTRATES WHICH CAN BE SOLDERED | ATOTECH Deutschland GmbH (DE) | 1997-09-17 | — | — | EP | disclosed |
| WO-1996016768-A1 | PROCESS FOR BONDING WIRES TO OXIDATION-SENSITIVE METAL SUBSTRATES WHICH CAN BE SOLDERED | ATOTECH DEUTSCHLAND GMBH (DE) | 1996-06-06 | — | — | WO | disclosed |
| EP-0619333-A2 | Process for coating metals | ATOTECH Deutschland GmbH (DE) | 1994-10-12 | — | — | EP | disclosed |