Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 1/20 | 0.42 |
| ▸ | FLT3 | P36888 | 1/20 | 0.40 |
| ▸ | KHK | P50053 | 1/20 | 0.37 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.35 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | GHSR | Q92847 | 1/20 | 0.34 |
| ▸ | IL1B | P01584 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | PBK | Q96KB5 | 1/20 | 0.33 |
| ▸ | FPR3 | P25089 | 1/20 | 0.33 |
| ▸ | FPR2 | P25090 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8397261 | 1.00 | ADORA2A (0.42) | ADORA2AFLT3KHKCHRNB4CHRNA3 | |
| SCHEMBL8393468 | 1.00 | ADORA2A (0.42) | ADORA2AFLT3KHKCHRNB4CHRNA3 | |
| SCHEMBL2096759 | 0.81 | EPHX1 (0.48) | ADORA2AKHKMEN1KMT2A | |
| SCHEMBL11036183 | 0.80 | EPHX1 (0.50) | KHKMEN1KMT2A | |
| SCHEMBL6242633 | 0.71 | SCN1A (0.33) | HTTMEN1KMT2A | |
| SCHEMBL7124281 | 0.70 | TERT (0.42) | KDM4EHTTMEN1KMT2A | |
| SCHEMBL8398430 | 0.69 | CA1 (0.43) | KDM4EHTTMEN1KMT2A | |
| SCHEMBL719291 | 0.68 | ADORA2A (0.40) | ADORA2AFLT3KHKHTTGHSR | |
| SCHEMBL714038 | 0.68 | ADORA2A (0.40) | ADORA2AFLT3KHKHTTGHSR | |
| SCHEMBL7259516 | 0.68 | EPHX2 (0.61) | ADORA2AKHKRAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0915834-A1 | METHOD AND COMPOSITIONS FOR PRODUCING ANALGESIA | ELAN PHARMACEUTICALS, INC. (US) | 1999-05-19 | — | — | EP | claimed |
| WO-1997033860-A1 | METHOD AND COMPOSITIONS FOR PRODUCING ANALGESIA | NEUREX CORPORATION (US) | 1997-09-18 | — | — | WO | claimed |
| EP-0915834-A1 | METHOD AND COMPOSITIONS FOR PRODUCING ANALGESIA | ELAN PHARMACEUTICALS, INC. (US) | 1999-05-19 | — | — | EP | disclosed |
| WO-1997033860-A1 | METHOD AND COMPOSITIONS FOR PRODUCING ANALGESIA | NEUREX CORPORATION (US) | 1997-09-18 | — | — | WO | disclosed |