Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPM1D | O15297 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18980367 | 0.83 | PPM1D (0.38) | PPM1D | |
| SCHEMBL20689390 | 0.76 | ARG1 (0.30) | — | |
| SCHEMBL838814 | 0.75 | PPM1D (0.35) | PPM1D | |
| SCHEMBL3126788 | 0.75 | PPM1D (0.35) | PPM1D | |
| SCHEMBL3568839 | 0.74 | PPM1D (0.37) | PPM1D | |
| Trifluoroacetic Acid SCHEMBL14761460 | 0.71 | PPM1D (0.34) | PPM1D | |
| SCHEMBL18980144 | 0.70 | PPM1D (0.35) | PPM1D | |
| SCHEMBL838807 | 0.70 | PPM1D (0.32) | PPM1D | |
| SCHEMBL838808 | 0.70 | PPM1D (0.32) | PPM1D | |
| SCHEMBL25405508 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8143263-B2 | Therapeutic agents | ASTRAZENECA AB (SE) | 2012-03-27 | — | — | US | disclosed |