SCHEMBL839871

SCHEMBL839871

CO[Si](OC)(OC)C(C)(Cl)c1ccc(CCl)cc1

nearest known ligand 0.30

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
HSP90AA1 P07900 1/20 0.30
HSP90AB1 P08238 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1580103 0.88
SCHEMBL841537 0.82
SCHEMBL841546 0.80
SCHEMBL840934 0.79 CA1 (0.32)
SCHEMBL1579855 0.76
SCHEMBL841793 0.74
SCHEMBL839887 0.74
SCHEMBL1204683 0.71 TSHR (0.48)
SCHEMBL10883198 0.71 ESR1 (0.46)
SCHEMBL9057542 0.71 CA1 (0.38)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2310446-B1 ACTIVATED HALO-CONTAINING ARALKYLSILANE MOMENTIVE PERFORMANCE MAT INC (US) 2015-12-23 EP claimed
CN-102177197-B Activated halo-containing aralkylsilane MOMENTIVE PERFORMANCE MAT INC 2013-11-06 CN claimed
US-8143336-B2 Activated halo-containing aralkylsilane composition, process of preparing same and rubber compositions made therefrom MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2012-03-27 US claimed
CN-102177197-A Activated halo-containing aralkylsilane MOMENTIVE PERFORMANCE MAT INC 2011-09-07 CN claimed
US-20100036018-A1 ACTIVATED HALO-CONTAINING ARALKYLSILANE COMPOSITION, PROCESS OF PREPARING SAME AND RUBBER COMPOSITIONS MADE THEREFROM MOMENTIVE PERFORMANCE MATERIALS INC. 2010-02-11 US claimed
EP-2310446-B1 ACTIVATED HALO-CONTAINING ARALKYLSILANE MOMENTIVE PERFORMANCE MAT INC (US) 2015-12-23 EP disclosed
CN-102177197-B Activated halo-containing aralkylsilane MOMENTIVE PERFORMANCE MAT INC 2013-11-06 CN disclosed
US-8143336-B2 Activated halo-containing aralkylsilane composition, process of preparing same and rubber compositions made therefrom MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2012-03-27 US disclosed
CN-102177197-A Activated halo-containing aralkylsilane MOMENTIVE PERFORMANCE MAT INC 2011-09-07 CN disclosed
EP-2310446-A1 ACTIVATED HALO-CONTAINING ARALKYLSILANE Momentive Performance Materials Inc. (US) 2011-04-20 EP disclosed
WO-2010017370-A1 ACTIVATED HALO-CONTAINING ARALKYLSILANE MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2010-02-11 WO disclosed
US-20100036018-A1 ACTIVATED HALO-CONTAINING ARALKYLSILANE COMPOSITION, PROCESS OF PREPARING SAME AND RUBBER COMPOSITIONS MADE THEREFROM MOMENTIVE PERFORMANCE MATERIALS INC. 2010-02-11 US disclosed