⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1579855 | 0.92 | — | — | |
| SCHEMBL841546 | 0.87 | — | — | |
| SCHEMBL1579780 | 0.85 | — | — | |
| SCHEMBL839887 | 0.85 | — | — | |
| SCHEMBL841793 | 0.85 | — | — | |
| SCHEMBL4444353 | 0.84 | — | — | |
| SCHEMBL839871 | 0.82 | HSP90AA1 (0.30) | — | |
| SCHEMBL840085 | 0.82 | TSHR (0.40) | — | |
| SCHEMBL1580103 | 0.82 | — | — | |
| SCHEMBL27849345 | 0.80 | MAPK1 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2310446-B1 | ACTIVATED HALO-CONTAINING ARALKYLSILANE | MOMENTIVE PERFORMANCE MAT INC (US) | 2015-12-23 | — | — | EP | claimed |
| CN-102177197-B | Activated halo-containing aralkylsilane | MOMENTIVE PERFORMANCE MAT INC | 2013-11-06 | — | — | CN | claimed |
| US-8143336-B2 | Activated halo-containing aralkylsilane composition, process of preparing same and rubber compositions made therefrom | MOMENTIVE PERFORMANCE MATERIALS INC. (US) | 2012-03-27 | — | — | US | claimed |
| CN-102177197-A | Activated halo-containing aralkylsilane | MOMENTIVE PERFORMANCE MAT INC | 2011-09-07 | — | — | CN | claimed |
| US-20100036018-A1 | ACTIVATED HALO-CONTAINING ARALKYLSILANE COMPOSITION, PROCESS OF PREPARING SAME AND RUBBER COMPOSITIONS MADE THEREFROM | MOMENTIVE PERFORMANCE MATERIALS INC. | 2010-02-11 | — | — | US | claimed |
| EP-2310446-B1 | ACTIVATED HALO-CONTAINING ARALKYLSILANE | MOMENTIVE PERFORMANCE MAT INC (US) | 2015-12-23 | — | — | EP | disclosed |
| CN-102177197-B | Activated halo-containing aralkylsilane | MOMENTIVE PERFORMANCE MAT INC | 2013-11-06 | — | — | CN | disclosed |
| US-8143336-B2 | Activated halo-containing aralkylsilane composition, process of preparing same and rubber compositions made therefrom | MOMENTIVE PERFORMANCE MATERIALS INC. (US) | 2012-03-27 | — | — | US | disclosed |
| CN-102177197-A | Activated halo-containing aralkylsilane | MOMENTIVE PERFORMANCE MAT INC | 2011-09-07 | — | — | CN | disclosed |
| US-20100036018-A1 | ACTIVATED HALO-CONTAINING ARALKYLSILANE COMPOSITION, PROCESS OF PREPARING SAME AND RUBBER COMPOSITIONS MADE THEREFROM | MOMENTIVE PERFORMANCE MATERIALS INC. | 2010-02-11 | — | — | US | disclosed |