Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | P2RX3 | P56373 | 2/20 | 0.33 |
| ▸ | LTB4R2 | Q9NPC1 | 3/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
| ▸ | PPARD | Q03181 | 1/20 | 0.32 |
| ▸ | PPARA | Q07869 | 1/20 | 0.32 |
| ▸ | AR | P10275 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | F10 | P00742 | 2/20 | 0.32 |
| ▸ | F2 | P00734 | 1/20 | 0.32 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8395601 | 0.91 | SMN1; SMN2 (0.41) | SMN1; SMN2P2RX3LTB4R2MAOB | |
| SCHEMBL8396324 | 0.91 | SMN1; SMN2 (0.41) | SMN1; SMN2LTB4R2MEN1KMT2ATDP1 | |
| SCHEMBL8399267 | 0.90 | SMN1; SMN2 (0.40) | SMN1; SMN2LTB4R2MAOB | |
| SCHEMBL8396071 | 0.90 | LTB4R2 (0.36) | LTB4R2PTGDR2LMNATP53 | |
| SCHEMBL8399206 | 0.90 | SMN1; SMN2 (0.40) | SMN1; SMN2LTB4R2TDP1PTGDR2LMNA | |
| SCHEMBL8399809 | 0.90 | SMN1; SMN2 (0.40) | SMN1; SMN2LTB4R2MEN1KMT2ATDP1 | |
| SCHEMBL8396412 | 0.90 | SMN1; SMN2 (0.40) | SMN1; SMN2LTB4R2MAOBPPARGPPARD | |
| SCHEMBL8399123 | 0.89 | SMN1; SMN2 (0.52) | SMN1; SMN2MEN1KMT2ATDP1L3MBTL1 | |
| SCHEMBL8396430 | 0.88 | SMN1; SMN2 (0.39) | SMN1; SMN2LTB4R2MEN1KMT2ATDP1 | |
| SCHEMBL8400345 | 0.88 | SMN1; SMN2 (0.40) | SMN1; SMN2LTB4R2MAOBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0647636-B1 | BENZOTHIAZOLE COMPOUND, PROCESS FOR PRODUCING THE SAME, AND USE THEREOF | SENJU PHARMA CO (JP) | 1999-06-09 | — | — | EP | disclosed |
| US-5532257-A | ENZYME INHIBITOR | SENJU PHARMACEUTICAL CO., LTD (JP) | 1996-07-02 | — | — | US | disclosed |
| EP-0647636-A1 | BENZOTHIAZOLE COMPOUND, PROCESS FOR PRODUCING THE SAME, AND USE THEREOF | Senju Pharmaceutical Co., Ltd. (JP) | 1995-04-12 | — | — | EP | disclosed |