Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.38 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | NOS2 | P35228 | 1/20 | 0.36 |
| ▸ | HSD17B1 | P14061 | 2/20 | 0.36 |
| ▸ | HSD17B2 | P37059 | 2/20 | 0.36 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8396412 | 0.93 | SMN1; SMN2 (0.40) | SMN1; SMN2KDM4EGAAHTTLTB4R2 | |
| SCHEMBL8395601 | 0.91 | SMN1; SMN2 (0.41) | SMN1; SMN2KDM4EMAPTNPC1LTB4R2 | |
| SCHEMBL8396324 | 0.91 | SMN1; SMN2 (0.41) | SMN1; SMN2KDM4EMAPTTDP1ALDH1A1 | |
| SCHEMBL8399267 | 0.90 | SMN1; SMN2 (0.40) | SMN1; SMN2MAPTALDH1A1NPC1GAA | |
| SCHEMBL8399115 | 0.90 | MTNR1A (0.40) | MTNR1AMTNR1BPTGDR2LMNANPC1 | |
| SCHEMBL8399271 | 0.90 | SMN1; SMN2 (0.39) | SMN1; SMN2MAPTALDH1A1HPGDLMNA | |
| SCHEMBL8399809 | 0.90 | SMN1; SMN2 (0.40) | SMN1; SMN2KDM4EMAPTTDP1PTGDR2 | |
| SCHEMBL8399030 | 0.90 | SMN1; SMN2 (0.40) | SMN1; SMN2TDP1PTGDR2LMNALTB4R2 | |
| SCHEMBL8399123 | 0.89 | SMN1; SMN2 (0.52) | SMN1; SMN2KDM4ETDP1HPGDGAA | |
| SCHEMBL8398076 | 0.89 | SMN1; SMN2 (0.39) | SMN1; SMN2MTNR1AMTNR1BKDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0647636-B1 | BENZOTHIAZOLE COMPOUND, PROCESS FOR PRODUCING THE SAME, AND USE THEREOF | SENJU PHARMA CO (JP) | 1999-06-09 | — | — | EP | disclosed |
| US-5532257-A | ENZYME INHIBITOR | SENJU PHARMACEUTICAL CO., LTD (JP) | 1996-07-02 | — | — | US | disclosed |
| EP-0647636-A1 | BENZOTHIAZOLE COMPOUND, PROCESS FOR PRODUCING THE SAME, AND USE THEREOF | Senju Pharmaceutical Co., Ltd. (JP) | 1995-04-12 | — | — | EP | disclosed |