Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1A1 | P14550 | 6/20 | 0.43 |
| ▸ | AKR1B1 | P15121 | 6/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8396330 | 0.94 | AKR1A1 (0.44) | AKR1A1AKR1B1SMN1; SMN2 | |
| SCHEMBL8397916 | 0.91 | AKR1A1 (0.42) | AKR1A1AKR1B1SMN1; SMN2 | |
| SCHEMBL8398956 | 0.91 | AKR1A1 (0.42) | AKR1A1AKR1B1SMN1; SMN2 | |
| SCHEMBL8396328 | 0.90 | AKR1B1 (0.42) | AKR1A1AKR1B1 | |
| SCHEMBL8400466 | 0.90 | AKR1A1 (0.49) | AKR1A1AKR1B1 | |
| SCHEMBL8395302 | 0.89 | AKR1A1 (0.41) | AKR1A1AKR1B1SMN1; SMN2 | |
| SCHEMBL8395597 | 0.89 | SMN1; SMN2 (0.51) | AKR1A1AKR1B1SMN1; SMN2 | |
| SCHEMBL8395304 | 0.86 | AKR1A1 (0.39) | AKR1A1AKR1B1 | |
| SCHEMBL8399112 | 0.86 | SMN1; SMN2 (0.40) | AKR1B1SMN1; SMN2 | |
| SCHEMBL8395635 | 0.85 | SMN1; SMN2 (0.39) | AKR1B1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-6279423-A | — | — | None | — | — | JP | disclosed |
| EP-0647636-B1 | BENZOTHIAZOLE COMPOUND, PROCESS FOR PRODUCING THE SAME, AND USE THEREOF | SENJU PHARMA CO (JP) | 1999-06-09 | — | — | EP | disclosed |
| US-5532257-A | ENZYME INHIBITOR | SENJU PHARMACEUTICAL CO., LTD (JP) | 1996-07-02 | — | — | US | disclosed |
| EP-0647636-A1 | BENZOTHIAZOLE COMPOUND, PROCESS FOR PRODUCING THE SAME, AND USE THEREOF | Senju Pharmaceutical Co., Ltd. (JP) | 1995-04-12 | — | — | EP | disclosed |
| JP-H06279423-A | BENZOTHIAZOLE DERIVATIVE, ITS PRODUCTION AND USE THEREOF | SENJU PHARMACEUT CO LTD | 1994-10-04 | — | — | JP | disclosed |