Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | LTB4R2 | Q9NPC1 | 6/20 | 0.38 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HK1 | P19367 | 1/20 | 0.34 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8398045 | 0.92 | SMN1; SMN2 (0.42) | SMN1; SMN2LTB4R2ALDH1A1KDM4EAKR1B1 | |
| SCHEMBL8400310 | 0.91 | SMN1; SMN2 (0.41) | SMN1; SMN2LTB4R2TRPM8ALDH1A1MAOB | |
| SCHEMBL8397106 | 0.90 | SMN1; SMN2 (0.40) | SMN1; SMN2LTB4R2ALDH1A1MAOBAKR1B1 | |
| SCHEMBL8396319 | 0.90 | SMN1; SMN2 (0.40) | SMN1; SMN2ALDH1A1HDAC6KDM4EAKR1B1 | |
| SCHEMBL8397981 | 0.89 | SMN1; SMN2 (0.40) | SMN1; SMN2LTB4R2TRPM8ALDH1A1HK1 | |
| SCHEMBL8396242 | 0.89 | SMN1; SMN2 (0.52) | SMN1; SMN2KDM4EAKR1B1MAPTMEN1 | |
| SCHEMBL8398046 | 0.89 | SMN1; SMN2 (0.39) | SMN1; SMN2ALDH1A1KDM4EMAPTGAA | |
| SCHEMBL8398973 | 0.89 | SMN1; SMN2 (0.39) | SMN1; SMN2LTB4R2MAOBAKR1B1 | |
| SCHEMBL8396282 | 0.88 | AKR1B1 (0.40) | LTB4R2HDAC1HDAC8HDAC6AKR1B1 | |
| SCHEMBL8399715 | 0.88 | SMN1; SMN2 (0.39) | SMN1; SMN2ALDH1A1HDAC6KDM4EAKR1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0647636-B1 | BENZOTHIAZOLE COMPOUND, PROCESS FOR PRODUCING THE SAME, AND USE THEREOF | SENJU PHARMA CO (JP) | 1999-06-09 | — | — | EP | disclosed |
| US-5532257-A | ENZYME INHIBITOR | SENJU PHARMACEUTICAL CO., LTD (JP) | 1996-07-02 | — | — | US | disclosed |
| EP-0647636-A1 | BENZOTHIAZOLE COMPOUND, PROCESS FOR PRODUCING THE SAME, AND USE THEREOF | Senju Pharmaceutical Co., Ltd. (JP) | 1995-04-12 | — | — | EP | disclosed |