Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8792783 | 0.98 | HTR1A (0.64) | HTR1ASLC6A4 | |
| SCHEMBL8396250 | 0.98 | HTR1A (0.64) | HTR1ASLC6A4 | |
| Oxalic Acid SCHEMBL8397820 | 0.94 | HTR1A (0.60) | HTR1ASLC6A4 | |
| SCHEMBL7885701 | 0.91 | HTR1A (0.59) | HTR1ASLC6A4 | |
| SCHEMBL5584644 | 0.91 | HTR1A (0.59) | HTR1ASLC6A4 | |
| SCHEMBL8397898 | 0.91 | HTR1A (0.55) | HTR1ASLC6A4 | |
| SCHEMBL8397985 | 0.90 | HTR1A (0.65) | HTR1ASLC6A4 | |
| SCHEMBL8399086 | 0.89 | HTR1A (0.54) | HTR1ASLC6A4 | |
| SCHEMBL8400226 | 0.88 | HTR1A (0.62) | HTR1ASLC6A4 | |
| Oxalic Acid SCHEMBL7814401 | 0.87 | HTR1A (0.55) | HTR1ASLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5912256-A | 0-(4-INDOLYLOXY)-3-(4-HYDROXY-4-NAPHTHYLPIPERIDIN-1-YL)PROPANE S | ELI LILLY AND COMPANY (US) | 1999-06-15 | — | — | US | disclosed |
| EP-0814084-A1 | Indole derivatives as 5-HT1A antagonists and as inhibitors of serotonine reuptake | ELI LILLY AND COMPANY (US) | 1997-12-29 | — | — | EP | disclosed |