Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 10/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | AKR1A1 | P14550 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8399128 | 0.93 | AKR1B1 (0.43) | AKR1B1 | |
| SCHEMBL8397936 | 0.91 | AKR1B1 (0.48) | AKR1B1GAA | |
| SCHEMBL8395765 | 0.90 | AKR1B1 (0.48) | AKR1B1 | |
| SCHEMBL8398008 | 0.90 | AKR1B1 (0.41) | AKR1B1GAAAKR1A1 | |
| SCHEMBL8397923 | 0.89 | AKR1B1 (0.42) | AKR1B1MEN1KMT2A | |
| SCHEMBL8400194 | 0.89 | AKR1B1 (0.40) | AKR1B1AKR1A1 | |
| SCHEMBL8395199 | 0.89 | SMN1; SMN2 (0.43) | AKR1B1MEN1KMT2A | |
| SCHEMBL8400507 | 0.89 | AKR1B1 (0.40) | AKR1B1GAA | |
| SCHEMBL8396238 | 0.89 | AKR1B1 (0.40) | AKR1B1GAA | |
| SCHEMBL8400237 | 0.89 | AKR1B1 (0.40) | AKR1B1GAAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0647636-B1 | BENZOTHIAZOLE COMPOUND, PROCESS FOR PRODUCING THE SAME, AND USE THEREOF | SENJU PHARMA CO (JP) | 1999-06-09 | — | — | EP | disclosed |
| US-5532257-A | ENZYME INHIBITOR | SENJU PHARMACEUTICAL CO., LTD (JP) | 1996-07-02 | — | — | US | disclosed |
| EP-0647636-A1 | BENZOTHIAZOLE COMPOUND, PROCESS FOR PRODUCING THE SAME, AND USE THEREOF | Senju Pharmaceutical Co., Ltd. (JP) | 1995-04-12 | — | — | EP | disclosed |