Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.49 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.49 |
| ▸ | HTR2B | P41595 | 1/20 | 0.49 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8399367 | 0.88 | MAPT (0.50) | MAPTMEN1NR1I2LMNACHRM2 | |
| SCHEMBL16933962 | 0.82 | L3MBTL1 (0.65) | MAPTMEN1NR1I2LMNACHRM2 | |
| SCHEMBL14339056 | 0.82 | L3MBTL1 (0.65) | MAPTMEN1NR1I2LMNACHRM2 | |
| SCHEMBL16933728 | 0.82 | L3MBTL1 (0.65) | MAPTMEN1NR1I2LMNACHRM2 | |
| SCHEMBL9992785 | 0.82 | L3MBTL1 (0.65) | MAPTMEN1NR1I2LMNACHRM2 | |
| SCHEMBL16933764 | 0.82 | L3MBTL1 (0.65) | MAPTMEN1NR1I2LMNACHRM2 | |
| SCHEMBL7956489 | 0.81 | MAPT (0.50) | MAPTMEN1NR1I2LMNACHRM2 | |
| SCHEMBL7956488 | 0.80 | MAPT (0.49) | MAPTMEN1NR1I2LMNACHRM2 | |
| SCHEMBL8376498 | 0.79 | MAPT (0.55) | MAPTMEN1NR1I2LMNACHRM2 | |
| SCHEMBL7954993 | 0.79 | L3MBTL1 (0.49) | MAPTMEN1NR1I2LMNACHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5968963-A | ADMINISTERING 1-(PHENYLMETHYL)-4-UNDECYL-5H-TETRAZOLE-5-IMINE TO PREVENT OR TREAT HYPERCHOLESTEROLEMIA | WARNER-LAMBERT COMPANY (US) | 1999-10-19 | — | — | US | disclosed |
| US-5578639-A | ANTICHOLESTEROL AGENTS | WARNER-LAMBERT COMPANY (US) | 1996-11-26 | — | — | US | disclosed |