Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F11 | P03951 | 1/20 | 0.47 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.47 |
| ▸ | HTR3B | O95264 | 1/20 | 0.47 |
| ▸ | HTR3A | P46098 | 1/20 | 0.47 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.47 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.47 |
| ▸ | GRIN2D | O15399 | 5/20 | 0.47 |
| ▸ | GRIN3B | O60391 | 5/20 | 0.47 |
| ▸ | GRIN1 | Q05586 | 5/20 | 0.47 |
| ▸ | GRIN2A | Q12879 | 5/20 | 0.47 |
| ▸ | GRIN2B | Q13224 | 5/20 | 0.47 |
| ▸ | GRIN2C | Q14957 | 5/20 | 0.47 |
| ▸ | GRIN3A | Q8TCU5 | 5/20 | 0.47 |
| ▸ | IDO1 | P14902 | 2/20 | 0.47 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | NOS3 | P29474 | 2/20 | 0.43 |
| ▸ | NOS1 | P29475 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1737052 | 0.82 | GRIN1 (0.62) | F11HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL7635935 | 0.79 | GRIN1 (0.54) | F11HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL4097844 | 0.77 | GRIN2D (0.52) | F11HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL9667523 | 0.77 | TAAR1 (0.71) | F11HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL4397637 | 0.76 | IDO1 (0.50) | IDO1ALDH1A1SMN1; SMN2RAB9A | |
| Hydrochloric Acid SCHEMBL19520756 | 0.75 | GRIN2D (0.55) | F11HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL4094076 | 0.74 | GRIN2D (0.54) | F11HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL13569807 | 0.72 | IDO1 (0.47) | IDO1ALDH1A1SMN1; SMN2HTTRAB9A | |
| SCHEMBL17351900 | 0.72 | GRIN2B (0.52) | F11HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL4093147 | 0.72 | GRIN2B (0.65) | F11HTR3EHTR3BHTR3AHTR3D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0918460-A1 | METHODS OF TREATMENT OF EYE TRAUMA AND DISORDERS | CAMBRIDGE NEUROSCIENCE, INC. (US) | 1999-06-02 | — | — | EP | disclosed |
| WO-1998004131-A1 | METHODS OF TREATMENT OF EYE TRAUMA AND DISORDERS | CAMBRIDGE NEUROSCIENCE, INC. (US) | 1998-02-05 | — | — | WO | disclosed |