Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN1 | Q05586 | 5/20 | 0.54 |
| ▸ | GRIN2B | Q13224 | 5/20 | 0.54 |
| ▸ | GRIN2D | O15399 | 4/20 | 0.54 |
| ▸ | GRIN3B | O60391 | 4/20 | 0.54 |
| ▸ | GRIN2A | Q12879 | 4/20 | 0.54 |
| ▸ | GRIN2C | Q14957 | 4/20 | 0.54 |
| ▸ | GRIN3A | Q8TCU5 | 4/20 | 0.54 |
| ▸ | F11 | P03951 | 1/20 | 0.49 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.48 |
| ▸ | HTR3B | O95264 | 1/20 | 0.48 |
| ▸ | HTR3A | P46098 | 1/20 | 0.48 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.48 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.48 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.47 |
| ▸ | HTR1A | P08908 | 1/20 | 0.47 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.47 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
| ▸ | DRD1 | P21728 | 1/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.47 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1737052 | 0.90 | GRIN1 (0.62) | GRIN1GRIN2BGRIN2DGRIN3BGRIN2A | |
| Sulfuric Acid SCHEMBL10891220 | 0.90 | LMNA (0.54) | GRIN1GRIN2BGRIN2DGRIN3BGRIN2A | |
| SCHEMBL4094076 | 0.81 | GRIN2D (0.54) | GRIN1GRIN2BGRIN2DGRIN3BGRIN2A | |
| SCHEMBL17351900 | 0.79 | GRIN2B (0.52) | GRIN1GRIN2BGRIN2DGRIN3BGRIN2A | |
| SCHEMBL4097844 | 0.79 | GRIN2D (0.52) | GRIN1GRIN2BGRIN2DGRIN3BGRIN2A | |
| SCHEMBL9667523 | 0.79 | TAAR1 (0.71) | GRIN1GRIN2BGRIN2DGRIN3BGRIN2A | |
| SCHEMBL8399381 | 0.79 | F11 (0.47) | GRIN1GRIN2BGRIN2DGRIN3BGRIN2A | |
| SCHEMBL45769 | 0.78 | GRIN2B (0.68) | GRIN1GRIN2BGRIN2DGRIN3BGRIN2A | |
| SCHEMBL6679015 | 0.77 | HTR3A (0.68) | GRIN1GRIN2BHTR3EHTR3BHTR3A | |
| Hydrochloric Acid SCHEMBL19520756 | 0.77 | GRIN2D (0.55) | GRIN1GRIN2BGRIN2DGRIN3BGRIN2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6399658-B1 | REDUCING DRUG SIDE EFFECT | SUMITOMO PHARMACEUTICALS CO., LTD. (JP) | 2002-06-04 | — | — | US | disclosed |
| EP-1004304-A1 | COMPOSITION CONTAINING ASCORBIC ACID | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 2000-05-31 | — | — | EP | disclosed |
| WO-1999052861-A1 | NOVEL BENZYL GUANIDINE DERIVATIVES FOR THERAPY AND IN-VIVO AND IN-VITRO DIAGNOSIS | Institut für Diagnostikforschung GmbH an der Freien Universität Berlin (DE) | 1999-10-21 | — | — | WO | disclosed |
| US-4622217-A | I-4-amino-3-iodobenzylguanidine as imaging and therapeutic agent | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 1986-11-11 | — | — | US | disclosed |
| US-4622217-A | I-4-amino-3-iodobenzylguanidine as imaging and therapeutic agent | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 1986-11-11 | — | — | US | disclosed |