Propionic Acid

Propionic Acid

SCHEMBL8399386

CCC(=O)O.CCC(=O)OSC

nearest known ligand 0.50

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Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
FFAR3 O14843 2/20 0.50
ALDH1A1 P00352 3/20 0.35
KDM6B O15054 1/20 0.33
KDM5C P41229 1/20 0.33
EGLN1 Q9GZT9 1/20 0.33
PHF8 Q9UPP1 1/20 0.33
KDM2A Q9Y2K7 1/20 0.33
NAAA Q02083 1/20 0.32
HDAC3 O15379 1/20 0.32
HDAC1 Q13547 1/20 0.32
HDAC2 Q92769 1/20 0.32
HDAC8 Q9BY41 1/20 0.32
TDP1 Q9NUW8 2/20 0.30
CYP2D6 P10635 1/20 0.30
TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1897520 0.92
SCHEMBL16599483 0.75 EGLN1 (0.54) FFAR3KDM6BKDM5CEGLN1PHF8
Propionic Acid SCHEMBL27609640 0.74
Propionic Acid SCHEMBL8939209 0.74
Propionic Acid SCHEMBL2493330 0.73 FFAR3 (0.62) FFAR3ALDH1A1KDM6BKDM5CEGLN1
SCHEMBL2767905 0.73 ALDH1A1 (0.41) FFAR3ALDH1A1NAAATDP1TSHR
SCHEMBL625367 0.73 ALDH1A1 (0.41) FFAR3ALDH1A1NAAATDP1TSHR
Propionic Acid SCHEMBL7897446 0.73 FFAR3 (0.62) FFAR3ALDH1A1KDM6BKDM5CEGLN1
Propionic Acid SCHEMBL28198350 0.72
Propionic Acid SCHEMBL29022826 0.72 FFAR3 (0.71) FFAR3ALDH1A1EGLN1HDAC3HDAC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3161528-B1 COMPOSITION FOR THE MANUFACTURE OF AN OPHTALMIC LENS COMPRISING AN UV-ABSORBER AND AN ANTI-YELLOWING ADDITIVE ESSILOR INT (FR) 2020-03-04 EP disclosed
US-10370520-B2 Composition for the manufacture of an ophthalmic lens comprising an UV-absorber and an anti-yellowing additive ESSILOR INTERNATIONAL (FR) 2019-08-06 US disclosed
US-20170121498-A1 Composition for the Manufacture of an Ophthalmic Lens Comprising an UV-Absorber and an Anti-Yellowing Additive ESSILOR INTERNATIONAL (FR) 2017-05-04 US disclosed
EP-3161528-A1 COMPOSITION FOR THE MANUFACTURE OF AN OPHTALMIC LENS COMPRISING AN UV-ABSORBER AND AN ANTI-YELLOWING ADDITIVE Essilor International (Compagnie Générale D'Optique) (FR) 2017-05-03 EP disclosed
EP-2960687-B1 COMPOSITION FOR THE MANUFACTURE OF AN OPHTALMIC LENS COMPRISING AN UV-ABSORBER AND AN ANTI-YELLOWING ADDITIVE ESSILOR INT (FR) 2016-09-21 EP disclosed
EP-2960687-A1 Composition for the manufacture of an ophtalmic lens comprising an uv-absorber and an anti-yellowing additive ESSILOR INTERNATIONAL (COMPAGNIE GENERALE D'OPTIQUE) (FR) 2015-12-30 EP disclosed
US-5919971-A REACTING HYDROGEN SULFIDE WITH THE CORRESPONDING ACRYLIC ACID ESTER IN PRESENCE OF A SOLID SUPPORT ELF ACQUITAINE EXPLORATION PRODUCTION FRANCE (FR) 1999-07-06 US disclosed
CN-1185431-A Process for synthesis of 3-mercaptoprapionic acid esters ELF AQUITAINE EXPLORATION PROD (FR) 1998-06-24 CN disclosed
US-4001181-A ACTINIC RADIATION STABILIZERS CIBA-GEIGY CORPORATION (US) 1977-01-04 US disclosed