Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6945199 | 0.81 | HTR1D (0.72) | HTR1DHTR1B | |
| SCHEMBL8401585 | 0.80 | HTR1D (0.50) | HTR1DHTR1B | |
| SCHEMBL8402669 | 0.80 | HTR1D (0.59) | HTR1DHTR1B | |
| SCHEMBL8401583 | 0.79 | HTR1D (0.51) | HTR1DHTR1B | |
| SCHEMBL8118432 | 0.78 | HTR1D (0.70) | HTR1DHTR1B | |
| SCHEMBL7479048 | 0.75 | HTR1D (1.00) | HTR1DHTR1B | |
| SCHEMBL4345892 | 0.75 | HTR1D (0.79) | HTR1DHTR1B | |
| SCHEMBL7908082 | 0.74 | HTR1D (0.77) | HTR1DHTR1B | |
| SCHEMBL7908080 | 0.74 | HTR1D (0.77) | HTR1DHTR1B | |
| SCHEMBL7474143 | 0.74 | HTR1D (1.00) | HTR1DHTR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5998415-A | Bicyclic heteroaryl-alkylene-(homo)piperazinones and thione analogues thereof, their preparation, and their use of as selective agonists of 5-HT1 -like receptors | MERCK SHARP & DOHME LTD. (GB) | 1999-12-07 | — | — | US | disclosed |
| WO-1997016446-A1 | BICYCLIC HETEROARYL-ALKYLENE-(HOMO)PIPERAZINONES AND THIONE ANALOGUES THEREOF, THEIR PREPARATION AND THEIR USE AS SELECTIVE AGONISTS OF 5-HT1-LIKE RECEPTORS | MERCK SHARP & DOHME LIMITED (GB) | 1997-05-09 | — | — | WO | disclosed |