Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8401583 | 0.85 | HTR1D (0.51) | HTR1DHTR1B | |
| SCHEMBL8402669 | 0.83 | HTR1D (0.59) | HTR1DHTR1B | |
| SCHEMBL8399415 | 0.80 | HTR1D (0.61) | HTR1DHTR1B | |
| SCHEMBL6945199 | 0.76 | HTR1D (0.72) | HTR1DHTR1B | |
| SCHEMBL6936730 | 0.69 | HTR1D (0.79) | HTR1DHTR1B | |
| SCHEMBL8781600 | 0.69 | HTR1D (0.74) | HTR1DHTR1B | |
| SCHEMBL8662335 | 0.68 | HTR1D (0.74) | HTR1DHTR1B | |
| SCHEMBL8662337 | 0.68 | HTR1D (0.81) | HTR1DHTR1B | |
| SCHEMBL4345892 | 0.68 | HTR1D (0.79) | HTR1DHTR1B | |
| SCHEMBL7908080 | 0.67 | HTR1D (0.77) | HTR1DHTR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5998415-A | Bicyclic heteroaryl-alkylene-(homo)piperazinones and thione analogues thereof, their preparation, and their use of as selective agonists of 5-HT1 -like receptors | MERCK SHARP & DOHME LTD. (GB) | 1999-12-07 | — | — | US | disclosed |