Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 12/20 | 0.45 |
| ▸ | MAPT | P10636 | 10/20 | 0.45 |
| ▸ | HPGD | P15428 | 8/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.45 |
| ▸ | POLB | P06746 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3840051 | 0.76 | MEN1 (0.38) | L3MBTL1MAPTHPGDMAPK1POLB | |
| SCHEMBL31200861 | 0.73 | SMN1; SMN2 (0.47) | L3MBTL1MAPTHPGDMAPK1CYP2C9 | |
| SCHEMBL29663904 | 0.71 | HTR2A (0.42) | L3MBTL1MAPTHPGDMAPK1POLB | |
| SCHEMBL20899378 | 0.71 | HTR2A (0.42) | L3MBTL1MAPTHPGDMAPK1POLB | |
| SCHEMBL8265598 | 0.70 | HPGD (0.50) | L3MBTL1MAPTHPGDMAPK1POLB | |
| SCHEMBL8420493 | 0.70 | KDM4E (0.60) | MAPTHPGDMAPK1POLBMEN1 | |
| SCHEMBL31437826 | 0.70 | KDM4E (0.60) | MAPTHPGDMAPK1POLBMEN1 | |
| SCHEMBL4510682 | 0.70 | MEN1 (0.33) | L3MBTL1POLBMEN1KMT2A | |
| SCHEMBL27285656 | 0.68 | MAPT (0.44) | L3MBTL1MAPTHPGDMAPK1POLB | |
| SCHEMBL6718819 | 0.68 | CA2 (0.47) | MAPTHPGDALDH1A1RAB9ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5929107-A | INHIBITORS OF ACYL-COA:CHOLESTEROL ACYLTRANSFERASE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1999-07-27 | — | — | US | disclosed |
| EP-0585913-B1 | Condensed heterocyclic compounds, their production and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1997-12-29 | — | — | EP | disclosed |
| US-5700810-A | Condensed heterocyclic compounds, their production and use | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1997-12-23 | — | — | US | disclosed |
| US-5492929-A | ENZYME INHIBITORS, ANTICHOLESTEROL AGENTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1996-02-20 | — | — | US | disclosed |
| US-5482967-A | LOWERING CHOLESTEROL | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1996-01-09 | — | — | US | disclosed |
| CN-1095718-A | Condensed heterocycle compound, their preparation and purposes | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1994-11-30 | — | — | CN | disclosed |
| CN-1090274-A | Condensed heterocyclic compounds and its preparation method and application | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1994-08-03 | — | — | CN | disclosed |
| EP-0602598-A1 | 3-Phenylindolyl-, -benzofuranyl- and -benzothienyl- alkylcarboxanilides, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1994-06-22 | — | — | EP | disclosed |
| EP-0585913-A2 | Condensed heterocyclic compounds, their production and use | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1994-03-09 | — | — | EP | disclosed |