Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.59 |
| ▸ | MAPT | P10636 | 2/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | HTT | P42858 | 1/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.59 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | EGFR | P00533 | 1/20 | 0.46 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.46 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.46 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.46 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8401001 | 0.92 | KMT2A (0.61) | ALDH1A1KMT2AMAPTHTTHSD17B10 | |
| SCHEMBL11591529 | 0.87 | KMT2A (0.60) | ALDH1A1KMT2AMAPTHSD17B10MEN1 | |
| SCHEMBL17616870 | 0.87 | KMT2A (0.60) | ALDH1A1KMT2AMAPTHSD17B10MEN1 | |
| SCHEMBL29292307 | 0.87 | KMT2A (0.54) | ALDH1A1KMT2AMAPTLMNAHTT | |
| SCHEMBL9807295 | 0.86 | MEN1 (0.56) | ALDH1A1KMT2AMAPTLMNAMEN1 | |
| SCHEMBL3945405 | 0.84 | HDAC1 (0.61) | ALDH1A1TDP1KDM4EHDAC1RAB9A | |
| SCHEMBL5036303 | 0.84 | CETP (0.56) | ALDH1A1KMT2AMAPTLMNAMEN1 | |
| SCHEMBL16236079 | 0.84 | CYP1A2 (0.54) | ALDH1A1KMT2AMAPTHSD17B10MEN1 | |
| SCHEMBL1826963 | 0.83 | CETP (0.58) | ALDH1A1KMT2ALMNAMEN1CYP1A2 | |
| SCHEMBL17702569 | 0.83 | CETP (0.58) | ALDH1A1KMT2ALMNAMEN1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0918754-A1 | ANTHRANILIC ACID DIAMIDES DERIVATIVES, THEIR PREPARATION AND PHARMACEUTICAL USE AS ANTI-GASTRIN AGENTS | ROTTA RESEARCH LABORATORIUM S.P.A. (IT) | 1999-06-02 | — | — | EP | disclosed |
| WO-1998000404-A1 | ANTHRANILIC ACID DIAMIDES DERIVATIVES, THEIR PREPARATION AND PHARMACEUTICAL USE AS ANTI-GASTRIN AGENTS | ROTTA RESEARCH LABORATORIUM S.P.A. (IT) | 1998-01-08 | — | — | WO | disclosed |