Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 1/20 | 0.61 |
| ▸ | PDE3B | Q13370 | 4/20 | 0.56 |
| ▸ | PDE3A | Q14432 | 4/20 | 0.56 |
| ▸ | P2RY12 | Q9H244 | 3/20 | 0.56 |
| ▸ | PPARG | P37231 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | PPARD | Q03181 | 2/20 | 0.56 |
| ▸ | PPARA | Q07869 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | PDE2A | O00408 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | CNR1 | P21554 | 1/20 | 0.52 |
| ▸ | CNR2 | P34972 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10785003 | 0.95 | HDAC1 (0.68) | HDAC1PDE3BPDE3AP2RY12PPARG | |
| SCHEMBL10902546 | 0.87 | PDE3B (0.53) | HDAC1PDE3BPDE3AP2RY12PDE2A | |
| SCHEMBL7632059 | 0.85 | CYSLTR2 (0.64) | HDAC1PDE3BPDE3AP2RY12PPARG | |
| SCHEMBL8399515 | 0.84 | ALDH1A1 (0.59) | HDAC1ALDH1A1KDM4ETDP1RAB9A | |
| SCHEMBL20886118 | 0.82 | PTPN7 (0.67) | HDAC1PDE3BPDE3AP2RY12PPARG | |
| SCHEMBL2474817 | 0.82 | PTPN7 (0.67) | PPARGALDH1A1PTPN7RAB9ANPC1 | |
| SCHEMBL30360394 | 0.82 | PTPN7 (0.67) | PPARGALDH1A1PTPN7RAB9ANPC1 | |
| SCHEMBL30539402 | 0.82 | PTPN7 (0.67) | HDAC1PDE3BPDE3AP2RY12PPARG | |
| SCHEMBL6328945 | 0.82 | HPGD (0.60) | HDAC1ALDH1A1TDP1RAB9ANPC1 | |
| SCHEMBL20897623 | 0.81 | HDAC1 (0.60) | HDAC1PPARGALDH1A1PPARDPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090280977-A1 | PROCESS FOR PREPARING CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS | BASELL POLIOLEFINE ITALIA S.R.L (IT) | 2009-11-12 | — | — | US | disclosed |
| EP-2051999-A1 | PROCESS FOR PREPARING CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS | Basell Poliolefine Italia S.r.l. (IT) | 2009-04-29 | — | — | EP | disclosed |
| WO-2008019802-A1 | PROCESS FOR PREPARING CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS | BASELL POLIOLEFINE ITALIA S.R.L. (DE) | 2008-02-21 | — | — | WO | disclosed |
| EP-0849291-B1 | Catalyst for olefin polymerization and method for preparing polyolefins | JAPAN POLYOLEFINS CO LTD (JP) | 2002-02-13 | — | — | EP | disclosed |
| US-6271167-B1 | TRIMETHOXYSILANE COMPOUND | JAPAN POLYOLEFINS CO., LTD. (JP) | 2001-08-07 | — | — | US | disclosed |
| EP-0717053-B1 | Catalyst for olefin polymerization and process for producing polyolefin using the same | JAPAN POLYOLEFINS CO LTD (JP) | 2001-03-14 | — | — | EP | disclosed |
| US-6096844-A | COMPRISING A TITANIUM COMPOUND, A MAGNESIUM COMPOUND, AND A HALOGEN COMPOUND, AN ORGANOALUMINUM COMPOUND, AN ORGANOSILICON COMPOUND | JAPAN POLYOLEFINS CO., LTD. (JP) | 2000-08-01 | — | — | US | disclosed |
| US-6063727-A | CATALYSTS WHICH ENABLE EFFICIENT PRODUCTION OF POLYOLEFINS HAVING LOW MOLECULAR WEIGHT, BROAD MOLECULAR WEIGHT DISTRIBUTION, HIGH STEREOREGULARITY | JAPAN POLYOLEFINS CO., LTD. (JP) | 2000-05-16 | — | — | US | disclosed |
| US-5849654-A | Catalyst for olefin polymerization and process for producing polyolefin using the same | JAPAN POLYOLEFINS CO., LTD. (JP) | 1998-12-15 | — | — | US | disclosed |
| EP-0849291-A1 | Catalyst for olefin polymerization and method for preparing polyolefins | Japan Polyolefins Co., Ltd. (JP) | 1998-06-24 | — | — | EP | disclosed |
| EP-0578473-B1 | Catalyst for polymerization of olefin and process for producing olefin polymer | SHOWA DENKO KK (JP) | 1997-11-19 | — | — | EP | disclosed |
| EP-0640624-B1 | Catalyst for polymerization of olefin and process for the preparation of olefin polymer | SHOWA DENKO KK (JP) | 1997-06-18 | — | — | EP | disclosed |
| EP-0717053-A2 | Catalyst for olefin polymerization and process for producing polyolefin using the same | JAPAN POLYOLEFINS CO., LTD. (JP) | 1996-06-19 | — | — | EP | disclosed |
| US-5476825-A | Consists of magnesium, titanium and halogen compounds, an organoaluminum compound, a reaction product of organoaluminum or organoboron compound with organosilicon compound | SHOWA DENKO K.K. (JP) | 1995-12-19 | — | — | US | disclosed |
| EP-0383346-B1 | Catalyst, process for its preparation and process for polymerization of olefins using this catalyst | SHOWA DENKO KK (JP) | 1995-05-03 | — | — | EP | disclosed |
| US-5407883-A | Containing magnesium, titanium, aluminum and silicon compounds including polymeric aluminum and alumoxanes | SHOWA DENKO K.K. (JP) | 1995-04-18 | — | — | US | disclosed |
| EP-0640624-A1 | Catalyst for polymerization of olefin and process for the preparation of olefin polymer | SHOWA DENKO KABUSHIKI KAISHA (JP) | 1995-03-01 | — | — | EP | disclosed |
| EP-0578473-A1 | Catalyst for polymerization of olefin and process for producing olefin polymer | SHOWA DENKO KABUSHIKI KAISHA (JP) | 1994-01-12 | — | — | EP | disclosed |
| US-5041403-A | Magnesium, titanium, halogen, ester compound, and organic aluminum compound | SHOWA DENKO K.K. (JP) | 1991-08-20 | — | — | US | disclosed |
| EP-0383346-A2 | Catalyst, process for its preparation and process for polymerization of olefins using this catalyst | SHOWA DENKO KABUSHIKI KAISHA (JP) | 1990-08-22 | — | — | EP | disclosed |