Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8399588 | 0.84 | EDNRB (0.43) | EDNRBEDNRA | |
| SCHEMBL8399581 | 0.77 | EDNRA (0.44) | EDNRBEDNRA | |
| SCHEMBL8395716 | 0.75 | EDNRB (0.57) | EDNRBEDNRA | |
| SCHEMBL8395730 | 0.73 | EDNRB (0.55) | EDNRBEDNRA | |
| SCHEMBL8399583 | 0.73 | EDNRA (0.51) | EDNRBEDNRA | |
| SCHEMBL7591508 | 0.71 | EDNRA (0.54) | EDNRBEDNRA | |
| SCHEMBL8397158 | 0.69 | EDNRA (0.49) | EDNRBEDNRA | |
| SCHEMBL7580836 | 0.69 | EDNRA (0.44) | EDNRBEDNRA | |
| SCHEMBL7598557 | 0.68 | EDNRA (0.51) | EDNRBEDNRA | |
| SCHEMBL8395719 | 0.68 | EDNRB (0.57) | EDNRBEDNRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5856484-A | Sulfonylaminopyrimidine carboxylic acid derivatives having endothelin inhibiting activity | HOFFMANN-LA ROCHE INC. (US) | 1999-01-05 | — | — | US | disclosed |