Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 6/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8395359 | 0.90 | AKR1B1 (0.36) | AKR1B1GAALMNA | |
| SCHEMBL8400510 | 0.88 | AKR1B1 (0.43) | AKR1B1GAALMNA | |
| SCHEMBL8396325 | 0.86 | HDAC6 (0.31) | AKR1B1GAAHDAC6 | |
| SCHEMBL8395543 | 0.85 | — | — | |
| SCHEMBL8396238 | 0.85 | AKR1B1 (0.40) | AKR1B1GAALMNA | |
| SCHEMBL8399299 | 0.80 | AKR1B1 (0.37) | AKR1B1LMNARAB9A | |
| SCHEMBL8399252 | 0.79 | AKR1B1 (0.36) | AKR1B1GAALMNAHDAC6 | |
| SCHEMBL8400193 | 0.79 | AKR1B1 (0.40) | AKR1B1GAALMNA | |
| SCHEMBL8399128 | 0.78 | AKR1B1 (0.43) | AKR1B1LMNA | |
| SCHEMBL8397936 | 0.78 | AKR1B1 (0.48) | AKR1B1GAALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0647636-B1 | BENZOTHIAZOLE COMPOUND, PROCESS FOR PRODUCING THE SAME, AND USE THEREOF | SENJU PHARMA CO (JP) | 1999-06-09 | — | — | EP | disclosed |
| US-5532257-A | ENZYME INHIBITOR | SENJU PHARMACEUTICAL CO., LTD (JP) | 1996-07-02 | — | — | US | disclosed |
| EP-0647636-A1 | BENZOTHIAZOLE COMPOUND, PROCESS FOR PRODUCING THE SAME, AND USE THEREOF | Senju Pharmaceutical Co., Ltd. (JP) | 1995-04-12 | — | — | EP | disclosed |