Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | NAAA | Q02083 | 1/20 | 0.30 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8396628 | 0.90 | P2RX3 (0.34) | SMN1; SMN2NPSR1L3MBTL1P2RX3 | |
| SCHEMBL8399211 | 0.88 | AKR1B1 (0.33) | HDAC6AKR1B1TP53 | |
| SCHEMBL8399620 | 0.86 | AKR1B1 (0.39) | HDAC6AKR1B1GAA | |
| SCHEMBL8399252 | 0.85 | AKR1B1 (0.36) | HDAC6AKR1B1GAASMN1; SMN2 | |
| SCHEMBL8400120 | 0.85 | LTB4R2 (0.37) | AKR1B1TP53L3MBTL1 | |
| SCHEMBL8395543 | 0.84 | — | — | |
| SCHEMBL8400517 | 0.80 | SMN1; SMN2 (0.34) | SMN1; SMN2NPSR1L3MBTL1NAAAP2RX3 | |
| SCHEMBL8396071 | 0.79 | LTB4R2 (0.36) | TP53 | |
| SCHEMBL8396435 | 0.79 | AKR1B1 (0.32) | AKR1B1NAAA | |
| SCHEMBL8395274 | 0.78 | AKR1B1 (0.37) | AKR1B1TP53GAASMN1; SMN2NAAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0647636-B1 | BENZOTHIAZOLE COMPOUND, PROCESS FOR PRODUCING THE SAME, AND USE THEREOF | SENJU PHARMA CO (JP) | 1999-06-09 | — | — | EP | disclosed |
| US-5532257-A | ENZYME INHIBITOR | SENJU PHARMACEUTICAL CO., LTD (JP) | 1996-07-02 | — | — | US | disclosed |
| EP-0647636-A1 | BENZOTHIAZOLE COMPOUND, PROCESS FOR PRODUCING THE SAME, AND USE THEREOF | Senju Pharmaceutical Co., Ltd. (JP) | 1995-04-12 | — | — | EP | disclosed |