Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VDR | P11473 | 7/20 | 0.49 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.40 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.40 |
| ▸ | PGR | P06401 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8401174 | 1.00 | VDR (0.49) | VDRADORA3SLC6A2NR1I2PGR | |
| SCHEMBL8400184 | 0.89 | VDR (0.49) | VDRADORA3SLC6A2NR1I2PGR | |
| SCHEMBL8400127 | 0.88 | VDR (0.47) | VDRADORA3SLC6A2NR1I2PGR | |
| SCHEMBL8398550 | 0.88 | VDR (0.47) | VDRADORA3SLC6A2NR1I2PGR | |
| SCHEMBL8401145 | 0.85 | VDR (0.48) | VDRADORA3SLC6A2NR1I2PGR | |
| SCHEMBL8400106 | 0.85 | VDR (0.48) | VDRADORA3SLC6A2NR1I2PGR | |
| SCHEMBL8616073 | 0.85 | VDR (0.67) | VDRADORA3SLC6A2NR1I2PGR | |
| SCHEMBL8400480 | 0.84 | VDR (0.69) | VDRADORA3SLC6A2NR1I2PGR | |
| SCHEMBL8397625 | 0.83 | VDR (0.48) | VDRADORA3SLC6A2NR1I2PGR | |
| SCHEMBL8973892 | 0.81 | VDR (0.51) | VDRADORA3SLC6A2NR1I2PGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0751932-B1 | VITAMIN-D AMIDE DERIVATIVES | RES INST MEDICINE CHEM (US) | 1999-06-09 | — | — | EP | disclosed |
| US-5811562-A | Vitamin-D amide derivatives | RESEARCH INSTITUTE FOR MEDICINE AND CHEMISTRY INC. (US) | 1998-09-22 | — | — | US | disclosed |
| EP-0751932-A1 | VITAMIN-D AMIDE DERIVATIVES | HOLMES, Michael John (GB) | 1997-01-08 | — | — | EP | disclosed |
| WO-1995025718-A1 | VITAMIN-D AMIDE DERIVATIVES | HOLMES, MICHAEL, JOHN (GB) | 1995-09-28 | — | — | WO | disclosed |