Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.53 |
| ▸ | MEN1 | O00255 | 5/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | GLA | P06280 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | KDR | P35968 | 5/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.47 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.47 |
| ▸ | CDK2 | P24941 | 1/20 | 0.47 |
| ▸ | ESR1 | P03372 | 1/20 | 0.47 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8402303 | 0.94 | KMT2A (0.50) | KMT2AMEN1GAASMN1; SMN2ALDH1A1 | |
| SCHEMBL8402296 | 0.87 | MEN1 (0.54) | KMT2AMEN1GAASMN1; SMN2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL8403682 | 0.86 | MEN1 (0.53) | KMT2AMEN1GAASMN1; SMN2ALDH1A1 | |
| SCHEMBL8594724 | 0.86 | MEN1 (0.53) | KMT2AMEN1GAASMN1; SMN2ALDH1A1 | |
| SCHEMBL8401838 | 0.84 | MEN1 (0.55) | KMT2AMEN1GAASMN1; SMN2ALDH1A1 | |
| SCHEMBL8399991 | 0.83 | ACP1 (0.54) | ESR1 | |
| Hydrochloric Acid SCHEMBL8399940 | 0.83 | ACP1 (0.53) | ESR1 | |
| SCHEMBL8403815 | 0.82 | MEN1 (0.53) | KMT2AMEN1GAASMN1; SMN2ALDH1A1 | |
| SCHEMBL8399903 | 0.80 | ACP1 (0.49) | ESR1 | |
| SCHEMBL7928850 | 0.79 | KDR (0.63) | KMT2AMEN1ALDH1A1KDM4EGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5929090-A | NOVEL COMPOUNDS FOR TREATING ESTROGEN DEPRIVATION CAUSED BY MENOPAUSE OR OVARIECTOMY; TREATING OSTEOPOROSIS, CARDIOVASCULAR DISEASES, AND ENDOMETRIOSIS | ELI LILLY AND COMPANY (US) | 1999-07-27 | — | — | US | disclosed |