Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.38 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | HBB | P68871 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8395843 | 0.92 | SMN1; SMN2 (0.51) | SMN1; SMN2MEN1KMT2AKDM4EATM | |
| SCHEMBL8396622 | 0.89 | SMN1; SMN2 (0.53) | SMN1; SMN2MEN1KMT2ACYP4F2CYP4A11 | |
| SCHEMBL8395306 | 0.89 | SMN1; SMN2 (0.53) | SMN1; SMN2MEN1KMT2AKDM4EATM | |
| SCHEMBL8395828 | 0.89 | SMN1; SMN2 (0.53) | SMN1; SMN2MEN1KMT2ACYP4F2CYP4A11 | |
| SCHEMBL8400320 | 0.89 | SMN1; SMN2 (0.46) | SMN1; SMN2KMT2AATMRAB9AALDH1A1 | |
| SCHEMBL8398077 | 0.89 | SMN1; SMN2 (0.72) | SMN1; SMN2MEN1KMT2AKDM4ECYP4F2 | |
| SCHEMBL8396419 | 0.88 | SMN1; SMN2 (0.52) | SMN1; SMN2KDM4EATMRAB9APOLB | |
| SCHEMBL8396219 | 0.87 | SMN1; SMN2 (0.51) | SMN1; SMN2MEN1KMT2AKDM4ECYP4F2 | |
| SCHEMBL8395198 | 0.87 | SMN1; SMN2 (0.51) | SMN1; SMN2MEN1KMT2AKDM4ECYP4F2 | |
| SCHEMBL8399243 | 0.87 | SMN1; SMN2 (0.51) | SMN1; SMN2MEN1KMT2ACYP4F2CYP4A11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0647636-B1 | BENZOTHIAZOLE COMPOUND, PROCESS FOR PRODUCING THE SAME, AND USE THEREOF | SENJU PHARMA CO (JP) | 1999-06-09 | — | — | EP | disclosed |
| US-5532257-A | ENZYME INHIBITOR | SENJU PHARMACEUTICAL CO., LTD (JP) | 1996-07-02 | — | — | US | disclosed |
| EP-0647636-A1 | BENZOTHIAZOLE COMPOUND, PROCESS FOR PRODUCING THE SAME, AND USE THEREOF | Senju Pharmaceutical Co., Ltd. (JP) | 1995-04-12 | — | — | EP | disclosed |