Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | CYP4F2 | P78329 | 3/20 | 0.35 |
| ▸ | CYP4A11 | Q02928 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8396258 | 0.92 | SMN1; SMN2 (0.42) | SMN1; SMN2ALDH1A1KDM4EMAPTMAPK1 | |
| SCHEMBL8399007 | 0.89 | SMN1; SMN2 (0.37) | SMN1; SMN2ALDH1A1KDM4EMAPTHSD17B10 | |
| SCHEMBL8400330 | 0.87 | SMN1; SMN2 (0.59) | SMN1; SMN2ALDH1A1KDM4EMAPTHSD17B10 | |
| SCHEMBL8395434 | 0.87 | SMN1; SMN2 (0.48) | SMN1; SMN2ALDH1A1KDM4EMAPTHSD17B10 | |
| SCHEMBL8399264 | 0.86 | SMN1; SMN2 (0.50) | SMN1; SMN2ALDH1A1KDM4EMAPTLMNA | |
| SCHEMBL8397040 | 0.85 | SMN1; SMN2 (0.46) | SMN1; SMN2ALDH1A1KDM4EMAPTHSD17B10 | |
| SCHEMBL8395828 | 0.85 | SMN1; SMN2 (0.53) | SMN1; SMN2ALDH1A1MAPTMAPK1LMNA | |
| SCHEMBL8396622 | 0.85 | SMN1; SMN2 (0.53) | SMN1; SMN2MAPTLMNATSHRCYP4F2 | |
| SCHEMBL8395306 | 0.85 | SMN1; SMN2 (0.53) | SMN1; SMN2ALDH1A1KDM4EMAPTLMNA | |
| SCHEMBL8398077 | 0.84 | SMN1; SMN2 (0.72) | SMN1; SMN2ALDH1A1KDM4ETSHRCYP4F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0647636-B1 | BENZOTHIAZOLE COMPOUND, PROCESS FOR PRODUCING THE SAME, AND USE THEREOF | SENJU PHARMA CO (JP) | 1999-06-09 | — | — | EP | disclosed |
| US-5532257-A | ENZYME INHIBITOR | SENJU PHARMACEUTICAL CO., LTD (JP) | 1996-07-02 | — | — | US | disclosed |
| EP-0647636-A1 | BENZOTHIAZOLE COMPOUND, PROCESS FOR PRODUCING THE SAME, AND USE THEREOF | Senju Pharmaceutical Co., Ltd. (JP) | 1995-04-12 | — | — | EP | disclosed |