Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | CA12 | O43570 | 1/20 | 0.51 |
| ▸ | CA1 | P00915 | 1/20 | 0.51 |
| ▸ | CA2 | P00918 | 1/20 | 0.51 |
| ▸ | ESR1 | P03372 | 1/20 | 0.51 |
| ▸ | CA7 | P43166 | 1/20 | 0.51 |
| ▸ | CA9 | Q16790 | 1/20 | 0.51 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.51 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | SCN1A | P35498 | 1/20 | 0.50 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.50 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | MAOA | P21397 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15561981 | 0.91 | TDP1 (0.62) | TDP1L3MBTL1MAPTCA12CA1 | |
| SCHEMBL3098710 | 0.91 | TDP1 (0.62) | TDP1L3MBTL1MAPTCA12CA1 | |
| SCHEMBL6279787 | 0.87 | CA12 (0.58) | TDP1L3MBTL1MAPTCA12CA1 | |
| Ethylparaben SCHEMBL10799572 | 0.87 | ESR1 (0.52) | TDP1L3MBTL1MAPTCA12CA1 | |
| SCHEMBL1503528 | 0.86 | MAPT (0.69) | TDP1L3MBTL1MAPTCA12CA1 | |
| SCHEMBL2877777 | 0.85 | TDP1 (0.55) | TDP1L3MBTL1MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL9929828 | 0.83 | ALDH1A1 (0.66) | TDP1L3MBTL1MAPTALDH1A1LMNA | |
| SCHEMBL4912817 | 0.82 | TDP1 (0.52) | TDP1L3MBTL1MAPTCA12CA1 | |
| SCHEMBL6701399 | 0.82 | TDP1 (0.74) | TDP1L3MBTL1MAPTCA12CA1 | |
| SCHEMBL5396072 | 0.82 | MAPT (0.63) | TDP1L3MBTL1MAPTCA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-8325252-A | — | — | None | — | — | JP | disclosed |
| US-5900426-A | ANTILIPEMIC AGENTS | NIPPON ZOKI PHARMACEUTICAL CO., LTD. (JP) | 1999-05-04 | — | — | US | disclosed |
| EP-0735029-B1 | Benzothiazole derivatives | NIPPON ZOKI PHARMACEUTICAL CO (JP) | 1998-06-03 | — | — | EP | disclosed |
| JP-H08325252-A | NEW BENZOTHIAZOLE DERIVATIVE | NIPPON ZOKI PHARMACEUT CO LTD | 1996-12-10 | — | — | JP | disclosed |
| EP-0735029-A1 | Benzothiazole derivatives | NIPPON ZOKI PHARMACEUTICAL CO., LTD. (JP) | 1996-10-02 | — | — | EP | disclosed |
| US-4698338-A | ANTIBIOTICS | ELI LILLY AND COMPANY (US) | 1987-10-06 | — | — | US | disclosed |
| EP-0233780-A2 | O-substituted oximino cephalosporins | ELI LILLY AND COMPANY (US) | 1987-08-26 | — | — | EP | disclosed |