SCHEMBL8400677

SCHEMBL8400677

CNC1CCCC1Oc1ccccc1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.55
THRB P10828 1/20 0.55
LMNA P02545 3/20 0.49
SMN1; SMN2 Q16637 2/20 0.46
SLC6A2 P23975 3/20 0.42
SLC6A3 Q01959 3/20 0.42
NPSR1 Q6W5P4 1/20 0.39
CARM1 Q86X55 1/20 0.39
PRMT6 Q96LA8 1/20 0.39
MMP2 P08253 5/20 0.38
MMP9 P14780 5/20 0.38
MMP13 P45452 5/20 0.38
MMP14 P50281 4/20 0.38
MMP7 P09237 2/20 0.38
MMP1 P03956 1/20 0.38
MMP3 P08254 1/20 0.38
HRH1 P35367 1/20 0.38
HCRTR2 O43614 1/20 0.38
SLC6A4 P31645 2/20 0.36
MAPK1 P28482 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8400676 1.00 ALDH1A1 (0.55) ALDH1A1THRBLMNASMN1; SMN2SLC6A2
SCHEMBL23067902 0.89 ALDH1A1 (0.46) ALDH1A1THRBLMNASMN1; SMN2SLC6A2
SCHEMBL7371715 0.85 KDM1A (0.47) ALDH1A1THRBLMNASMN1; SMN2SLC6A2
SCHEMBL7371716 0.85 KDM1A (0.47) ALDH1A1THRBLMNASMN1; SMN2SLC6A2
SCHEMBL8396506 0.85 KDM1A (0.47) ALDH1A1THRBLMNASMN1; SMN2SLC6A2
SCHEMBL8396505 0.85 KDM1A (0.47) ALDH1A1THRBLMNASMN1; SMN2SLC6A2
SCHEMBL7371720 0.85 KDM1A (0.47) ALDH1A1THRBLMNASMN1; SMN2SLC6A2
Hydrochloric Acid SCHEMBL7454460 0.84 KDM1A (0.46) ALDH1A1THRBLMNASMN1; SMN2SLC6A2
SCHEMBL20995905 0.80 ALDH1A1 (0.50) ALDH1A1THRBLMNASLC6A2SLC6A3
SCHEMBL23074622 0.78 ALDH1A1 (0.55) ALDH1A1THRBLMNASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250345785-A1 ANIONIC EXCHANGE-HYDROPHOBIC MIXED MODE CHROMATOGRAPHY RESINS BIO RAD LABORATORIES INC (US) 2025-11-13 US claimed
US-11896969-B2 Anionic exchange-hydrophobic mixed mode chromatography resins BIO-RAD LABORATORIES, INC. (US) 2024-02-13 US claimed
US-20250345785-A1 ANIONIC EXCHANGE-HYDROPHOBIC MIXED MODE CHROMATOGRAPHY RESINS BIO RAD LABORATORIES INC (US) 2025-11-13 US disclosed
US-12364978-B2 Anionic exchange-hydrophobic mixed mode chromatography resins BIO-RAD LABORATORIES, INC. (US) 2025-07-22 US disclosed
US-20240261775-A1 ANIONIC EXCHANGE-HYDROPHOBIC MIXED MODE CHROMATOGRAPHY RESINS BIO-RAD LABORATORIES, INC. 2024-08-08 US disclosed
US-11896969-B2 Anionic exchange-hydrophobic mixed mode chromatography resins BIO-RAD LABORATORIES, INC. (US) 2024-02-13 US disclosed
WO-2021046284-A1 ANIONIC EXCHANGE-HYDROPHOBIC MIXED MODE CHROMATOGRAPHY RESINS BIO-RAD LABORATORIES, INC. (US) 2021-03-11 WO disclosed
US-20210069692-A1 ANIONIC EXCHANGE-HYDROPHOBIC MIXED MODE CHROMATOGRAPHY RESINS BIO-RAD LABORATORIES, INC. 2021-03-11 US disclosed
US-20210069692-A1 ANIONIC EXCHANGE-HYDROPHOBIC MIXED MODE CHROMATOGRAPHY RESINS BIO-RAD LABORATORIES, INC. 2021-03-11 US disclosed
EP-0752981-B1 SUBSTITUTED CYCLOPENTYLAMINE DERIVATIVES AND THEIR USE AS CALCIUM CHANNEL ANTAGONISTS SMITHKLINE BEECHAM PLC (GB) 1999-06-09 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250345785-A1 ANIONIC EXCHANGE-HYDROPHOBIC MIXED MODE CHROMATOGRAPHY RESINS ABCG2, SLC7A1, MSR1 ALDH1A1 4738/4885THRB 3260/4885LMNA 1875/4885
US-12364978-B2 Anionic exchange-hydrophobic mixed mode chromatography resins ABCG2, SLC7A1, MSR1 ALDH1A1 4738/4885THRB 3260/4885LMNA 1875/4885
US-20240261775-A1 ANIONIC EXCHANGE-HYDROPHOBIC MIXED MODE CHROMATOGRAPHY RESINS ABCG2, SLC7A1, MSR1 ALDH1A1 4738/4885THRB 3260/4885LMNA 1875/4885
US-20210069692-A1 ANIONIC EXCHANGE-HYDROPHOBIC MIXED MODE CHROMATOGRAPHY RESINS ABCG2, SLC7A1, MSR1 ALDH1A1 4738/4885THRB 3260/4885LMNA 1875/4885
US-11896969-B2 Anionic exchange-hydrophobic mixed mode chromatography resins ABCG2, SLC7A1, MSR1 ALDH1A1 4738/4885THRB 3260/4885LMNA 1875/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.