⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8428530 | 0.88 | — | — | |
| SCHEMBL6156344 | 0.80 | — | — | |
| SCHEMBL8398462 | 0.76 | — | — | |
| SCHEMBL6156138 | 0.70 | EPHX2 (0.35) | — | |
| SCHEMBL8400949 | 0.66 | — | — | |
| SCHEMBL8519721 | 0.65 | — | — | |
| SCHEMBL8916532 | 0.65 | EPHX2 (0.35) | — | |
| SCHEMBL8519519 | 0.65 | CNR2 (0.33) | — | |
| SCHEMBL8885683 | 0.64 | C1S (0.30) | — | |
| SCHEMBL8401612 | 0.64 | KDM4E (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0918460-A1 | METHODS OF TREATMENT OF EYE TRAUMA AND DISORDERS | CAMBRIDGE NEUROSCIENCE, INC. (US) | 1999-06-02 | — | — | EP | disclosed |
| WO-1998004131-A1 | METHODS OF TREATMENT OF EYE TRAUMA AND DISORDERS | CAMBRIDGE NEUROSCIENCE, INC. (US) | 1998-02-05 | — | — | WO | disclosed |