Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 16/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | FAAH | O00519 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6156344 | 0.81 | — | — | |
| SCHEMBL6154894 | 0.74 | EPHX2 (0.38) | EPHX2MAPK1HPGDCNR2FAAH | |
| SCHEMBL6154718 | 0.68 | EPHX2 (0.41) | EPHX2MAPK1LMNAALDH1A1MAPT | |
| SCHEMBL6155273 | 0.67 | EPHX2 (0.38) | EPHX2MAPK1LMNAALDH1A1MAPT | |
| SCHEMBL6157063 | 0.67 | EPHX2 (0.38) | EPHX2MAPK1LMNAALDH1A1FAAH | |
| SCHEMBL8428530 | 0.66 | — | — | |
| SCHEMBL6154614 | 0.65 | EPHX2 (0.38) | EPHX2 | |
| SCHEMBL6156235 | 0.65 | EPHX2 (0.42) | EPHX2LMNAALDH1A1MAPTHPGD | |
| SCHEMBL8400958 | 0.65 | — | — | |
| SCHEMBL6156328 | 0.64 | L3MBTL1 (0.42) | EPHX2MAPK1LMNAALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5622968-A | ADMINISTERING TO BLOCK VOLTAGE SENSITIVE CALCIUM CHANNELS OF MAMMALIAN NEURONAL CELLS | CAMBRIDGE NEUROSCIENCE, INC. (US) | 1997-04-22 | — | — | US | disclosed |