Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCKBR | P32239 | 20/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8401005 | 0.90 | CCKBR (0.65) | CCKBR | |
| SCHEMBL8921786 | 0.87 | CCKBR (0.62) | CCKBR | |
| SCHEMBL8398527 | 0.86 | CCKBR (0.48) | CCKBR | |
| SCHEMBL8981698 | 0.84 | CCKBR (0.48) | CCKBR | |
| SCHEMBL8402111 | 0.80 | CCKBR (0.65) | CCKBR | |
| SCHEMBL8398586 | 0.79 | CCKBR (0.65) | CCKBR | |
| SCHEMBL8398590 | 0.78 | CCKBR (1.00) | CCKBR | |
| SCHEMBL8922722 | 0.77 | CCKBR (0.55) | CCKBR | |
| SCHEMBL8398534 | 0.76 | CCKBR (0.48) | CCKBR | |
| SCHEMBL8919449 | 0.76 | CCKBR (0.84) | CCKBR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0711283-B1 | TETRAHYDRO-1H-BENZAZEPINONES AND HEXAHYDROAZEPINONES AS SELECTIVE CHOLECYSTOKININ-B RECEPTOR ANTAGONISTS | PFIZER (US) | 1999-06-16 | — | — | EP | disclosed |
| US-5618811-A | Tetrahydro-1H-benzazepinones and hexahydroazepinones as selective cholecystokinin-B receptor antagonists | PFIZER INC. (US) | 1997-04-08 | — | — | US | disclosed |
| EP-0711283-A1 | TETRAHYDRO-1H-BENZAZEPINONES AND HEXAHYDROAZEPINONES AS SELECTIVE CHOLECYSTOKININ-B RECEPTOR ANTAGONISTS | PFIZER INC. (US) | 1996-05-15 | — | — | EP | disclosed |
| WO-1995003281-A1 | TETRAHYDRO-1H-BENZAZEPINONES AND HEXAHYDROAZEPINONES AS SELECTIVE CHOLECYSTOKININ-B RECEPTOR ANTAGONISTS | PFIZER INC. (US) | 1995-02-02 | — | — | WO | disclosed |