Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NUDT1 | P36639 | 5/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12433234 | 0.81 | MAPK1 (0.36) | MAPK1ALDH1A1 | |
| SCHEMBL14213292 | 0.77 | MAPK1 (0.36) | MAPK1ALDH1A1 | |
| SCHEMBL16883925 | 0.77 | MAPK1 (0.36) | MAPK1ALDH1A1 | |
| SCHEMBL284757 | 0.75 | NUDT1 (0.34) | NUDT1MAPK1 | |
| SCHEMBL8997493 | 0.75 | NUDT1 (0.34) | NUDT1 | |
| SCHEMBL22746749 | 0.74 | CYP4F2 (0.35) | NUDT1 | |
| SCHEMBL10308085 | 0.74 | NUDT1 (0.33) | NUDT1 | |
| SCHEMBL10658831 | 0.73 | — | — | |
| SCHEMBL818866 | 0.73 | — | — | |
| SCHEMBL284223 | 0.73 | TSHR (0.37) | NUDT1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0133881-A1 | Aliphatic monoethers of 2,2-dimethylpropane-1,3-diol with C3 to C20 alkoxy groups, with the exception of 3-isopropoxy-2,2-dimethylpropane-1-ol and 3-tert.butoxy-2,2-dimethylpropane-1-ol, process for their production and their use as plasticizer alcohols | HÜLS AKTIENGESELLSCHAFT (DE) | 1985-03-13 | — | — | EP | claimed |
| US-9718825-B2 | N-(4-(azaindazol-6-yl)-phenyl)-sulfonamides and their use as pharmaceuticals | SANOFI (FR) | 2017-08-01 | — | — | US | disclosed |
| US-20160024097-A1 | N-(4-(AZAINDAZOL-6-YL)-PHENYL)-SULFONAMIDES AND THEIR USE AS PHARMACEUTICALS | SANOFI (FR) | 2016-01-28 | — | — | US | disclosed |
| US-8987251-B2 | Triazolopyridine compounds as PIM kinase inhibitors | ARRAY BIOPHARMA INC. (US) | 2015-03-24 | — | — | US | disclosed |
| US-20140045817-A1 | TRIAZOLOPYRIDINE COMPOUNDS AS PIM KINASE INHIBITORS | ARRAY BIOPHARMA INC. (US) | 2014-02-13 | — | — | US | disclosed |
| US-8575145-B2 | Triazolopyridine compounds as PIM kinase inhibitors | ARRAY BIOPHARMA INC. (US) | 2013-11-05 | — | — | US | disclosed |
| WO-2012081736-A1 | CONTINUOUS ARYCYCLIC COMPOUND | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2012-06-21 | — | — | WO | disclosed |
| US-8202677-B2 | Chemically-amplified positive resist composition and patterning process thereof | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2012-06-19 | — | — | US | disclosed |
| US-20110144085-A1 | TRIAZOLOPYRIDINE COMPOUNDS AS PIM KINASE INHIBITORS | ARRAY BIOPHARMA INC. (US) | 2011-06-16 | — | — | US | disclosed |
| US-20100009286-A1 | Chemically-amplified positive resist composition and patterning process thereof | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2010-01-14 | — | — | US | disclosed |
| EP-0733618-B1 | Monocarbonates, use thereof and process for the preparation of compositions containing monocarbonates | MITSUI CHEMICALS INC (JP) | 1999-06-09 | — | — | EP | disclosed |
| US-5656578-A | COMPATIBLE LUBRICATING OIL; DIELECTRICS, CLEANING PROPERTY | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1997-08-12 | — | — | US | disclosed |
| EP-0733618-A2 | Monocarbonates, use thereof and process for the preparation of compositions containing monocarbonates | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1996-09-25 | — | — | EP | disclosed |
| EP-0133881-A1 | Aliphatic monoethers of 2,2-dimethylpropane-1,3-diol with C3 to C20 alkoxy groups, with the exception of 3-isopropoxy-2,2-dimethylpropane-1-ol and 3-tert.butoxy-2,2-dimethylpropane-1-ol, process for their production and their use as plasticizer alcohols | HÜLS AKTIENGESELLSCHAFT (DE) | 1985-03-13 | — | — | EP | disclosed |
| EP-0133881-A1 | Aliphatic monoethers of 2,2-dimethylpropane-1,3-diol with C3 to C20 alkoxy groups, with the exception of 3-isopropoxy-2,2-dimethylpropane-1-ol and 3-tert.butoxy-2,2-dimethylpropane-1-ol, process for their production and their use as plasticizer alcohols | HÜLS AKTIENGESELLSCHAFT (DE) | 1985-03-13 | — | — | EP | disclosed |
| EP-0133881-A1 | Aliphatic monoethers of 2,2-dimethylpropane-1,3-diol with C3 to C20 alkoxy groups, with the exception of 3-isopropoxy-2,2-dimethylpropane-1-ol and 3-tert.butoxy-2,2-dimethylpropane-1-ol, process for their production and their use as plasticizer alcohols | HÜLS AKTIENGESELLSCHAFT (DE) | 1985-03-13 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160024097-A1 | N-(4-(AZAINDAZOL-6-YL)-PHENYL)-SULFONAMIDES AND THEIR USE AS PHARMACEUTICALS | SGK1, SGK3, SGK2 | NUDT1 4675/4885MAPK1 237/4885ALDH1A1 3312/4885 |
| US-20110144085-A1 | TRIAZOLOPYRIDINE COMPOUNDS AS PIM KINASE INHIBITORS | PIM1, PIM2, PIM3 | NUDT1 3926/4885MAPK1 73/4885ALDH1A1 2440/4885 |
| US-20140045817-A1 | TRIAZOLOPYRIDINE COMPOUNDS AS PIM KINASE INHIBITORS | PIM2, PIM1, PIM3 | NUDT1 3442/4885MAPK1 81/4885ALDH1A1 1820/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.