Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 7/20 | 0.53 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.53 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.53 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.53 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.53 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.53 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.53 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | CXCR4 | P61073 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6721189 | 0.86 | SIGMAR1 (0.65) | SIGMAR1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL6720949 | 0.81 | SIGMAR1 (0.64) | SIGMAR1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL6720839 | 0.81 | SIGMAR1 (0.53) | SIGMAR1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL6719157 | 0.80 | SIGMAR1 (0.61) | SIGMAR1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL7377504 | 0.79 | SIGMAR1 (0.55) | SIGMAR1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL6724578 | 0.77 | SIGMAR1 (0.54) | SIGMAR1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL8401127 | 0.77 | KMT2A (0.57) | KMT2AMEN1POLBALDH1A1HPGD | |
| SCHEMBL6720695 | 0.77 | SIGMAR1 (0.64) | SIGMAR1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL6724316 | 0.76 | SIGMAR1 (0.57) | SIGMAR1GRIN2DGRIN3BGRIN1GRIN2A | |
| Hydrochloric Acid SCHEMBL8500501 | 0.76 | SIGMAR1 (0.56) | SIGMAR1GRIN2DGRIN3BGRIN1GRIN2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0918460-A1 | METHODS OF TREATMENT OF EYE TRAUMA AND DISORDERS | CAMBRIDGE NEUROSCIENCE, INC. (US) | 1999-06-02 | — | — | EP | claimed |
| WO-1998004131-A1 | METHODS OF TREATMENT OF EYE TRAUMA AND DISORDERS | CAMBRIDGE NEUROSCIENCE, INC. (US) | 1998-02-05 | — | — | WO | claimed |