Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 14/20 | 0.46 |
| ▸ | GRIN2D | O15399 | 4/20 | 0.43 |
| ▸ | GRIN3B | O60391 | 4/20 | 0.43 |
| ▸ | GRIN1 | Q05586 | 4/20 | 0.43 |
| ▸ | GRIN2A | Q12879 | 4/20 | 0.43 |
| ▸ | GRIN2B | Q13224 | 4/20 | 0.43 |
| ▸ | GRIN2C | Q14957 | 4/20 | 0.43 |
| ▸ | GRIN3A | Q8TCU5 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.36 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.33 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6154735 | 0.87 | SIGMAR1 (0.48) | SIGMAR1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL6719463 | 0.81 | SIGMAR1 (0.51) | SIGMAR1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL6716825 | 0.79 | SIGMAR1 (0.50) | SIGMAR1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL6720347 | 0.77 | MAPT (0.47) | SIGMAR1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL6720666 | 0.77 | MAPT (0.49) | SIGMAR1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL4076514 | 0.76 | SMN1; SMN2 (0.73) | SIGMAR1GRIN2DGRIN3BGRIN1GRIN2A | |
| Hydrochloric Acid SCHEMBL21645383 | 0.76 | SIGMAR1 (0.49) | SIGMAR1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL6154964 | 0.76 | SIGMAR1 (0.55) | SIGMAR1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL8332997 | 0.75 | SIGMAR1 (0.55) | SIGMAR1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL6724652 | 0.73 | HSD17B10 (0.46) | SIGMAR1ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0918460-A1 | METHODS OF TREATMENT OF EYE TRAUMA AND DISORDERS | CAMBRIDGE NEUROSCIENCE, INC. (US) | 1999-06-02 | — | — | EP | claimed |
| WO-1998004131-A1 | METHODS OF TREATMENT OF EYE TRAUMA AND DISORDERS | CAMBRIDGE NEUROSCIENCE, INC. (US) | 1998-02-05 | — | — | WO | claimed |