Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 2/20 | 0.46 |
| ▸ | TACR3 | P29371 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 4/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.42 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | FAAH | O00519 | 1/20 | 0.41 |
| ▸ | MGLL | Q99685 | 1/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | CASP7 | P55210 | 1/20 | 0.41 |
| ▸ | MIF | P14174 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7297137 | 0.92 | NPC1 (0.48) | ELANERAB9ANPC1ALDH1A1SMN1; SMN2 | |
| SCHEMBL8405741 | 0.90 | TRPV1 (0.48) | ELANERAB9ANPC1MAPTSMN1; SMN2 | |
| SCHEMBL8403664 | 0.88 | SCD (0.48) | ELANERAB9ANPC1MAPTSMN1; SMN2 | |
| SCHEMBL7292947 | 0.88 | ELANE (0.45) | ELANERAB9ANPC1SMN1; SMN2POLB | |
| SCHEMBL8401233 | 0.88 | POLB (0.53) | ELANERAB9ANPC1POLBCASP3 | |
| SCHEMBL8401497 | 0.85 | NPC1 (0.47) | ELANERAB9ANPC1MAPTSMN1; SMN2 | |
| SCHEMBL7294413 | 0.85 | NAMPT (0.47) | ELANERAB9ANPC1ALDH1A1MAPT | |
| SCHEMBL8405850 | 0.85 | ELANE (0.47) | ELANERAB9ANPC1ATMALDH1A1 | |
| SCHEMBL8405275 | 0.83 | NPC1 (0.53) | ELANERAB9ANPC1ALDH1A1MAPT | |
| SCHEMBL8403691 | 0.82 | ELANE (0.43) | ELANETACR3RAB9ANPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5948785-A | USEFUL AS CHYMASE INHIBITORS AND CAN BE EFFECTIVE FOR THE PROPHYLAXIS AND TREATMENT OF VARIOUS DISEASES CAUSED BY CHYMASE, SUCH AS THOSE CAUSED BY ANGIOTENSIN II. | THE GREEN CROSS CORPORATION (JP) | 1999-09-07 | — | — | US | disclosed |