Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C2 | P52895 | 1/20 | 0.70 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.63 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.63 |
| ▸ | HTR1D | P28221 | 2/20 | 0.55 |
| ▸ | HTR6 | P50406 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 4/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.54 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.54 |
| ▸ | HTR1A | P08908 | 1/20 | 0.53 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.53 |
| ▸ | HTR1E | P28566 | 1/20 | 0.53 |
| ▸ | HTR7 | P34969 | 1/20 | 0.53 |
| ▸ | HTR5A | P47898 | 1/20 | 0.53 |
| ▸ | HDAC1 | Q13547 | 5/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7960856 | 0.88 | AKR1C2 (0.67) | AKR1C2MTNR1AMTNR1BHTR1DHTR6 | |
| Deboxamet SCHEMBL186946 | 0.87 | AKR1C2 (0.74) | AKR1C2MTNR1AMTNR1BHTR1DHTR6 | |
| SCHEMBL8270880 | 0.87 | AKR1C2 (0.74) | AKR1C2MTNR1AMTNR1BHTR1DHTR6 | |
| Deboxamet SCHEMBL29387753 | 0.87 | AKR1C2 (0.74) | AKR1C2MTNR1AMTNR1BHTR1DHTR6 | |
| SCHEMBL8110763 | 0.85 | AKR1C2 (0.70) | AKR1C2MTNR1AMTNR1BHTR1DHTR6 | |
| SCHEMBL7696769 | 0.85 | AKR1C2 (0.67) | AKR1C2MTNR1AMTNR1BKDM4EHDAC1 | |
| SCHEMBL30604527 | 0.84 | AKR1C2 (0.78) | AKR1C2MTNR1AMTNR1BHTR1DHTR6 | |
| SCHEMBL6825151 | 0.84 | AKR1C2 (0.78) | AKR1C2MTNR1AMTNR1BHTR1DHTR6 | |
| SCHEMBL17447391 | 0.83 | AKR1C2 (0.61) | AKR1C2MTNR1AMTNR1BHTR1DHTR6 | |
| SCHEMBL8587020 | 0.83 | AKR1C2 (0.61) | AKR1C2MTNR1AMTNR1BHTR1DHTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070293530-A1 | SULFAMIDE AND SULFAMATE DERIVATIVES AS HISTONE DEACETYLASE INHIBITORS | METHYLGENE INC. (CA) | 2007-12-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070293530-A1 | SULFAMIDE AND SULFAMATE DERIVATIVES AS HISTONE DEACETYLASE INHIBITORS | HDAC1, HDAC11, HAT1 | AKR1C2 1101/4885MTNR1A 683/4885MTNR1B 1186/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.