Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.55 |
| ▸ | MAPT | P10636 | 4/20 | 0.55 |
| ▸ | LMNA | P02545 | 3/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | RECQL | P46063 | 1/20 | 0.55 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.53 |
| ▸ | DUSP3 | P51452 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 3/20 | 0.49 |
| ▸ | HPGD | P15428 | 3/20 | 0.49 |
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.49 |
| ▸ | RAD52 | P43351 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8403887 | 0.83 | HSD17B1 (0.49) | MEN1KMT2AMAPTLMNAKDM4E | |
| SCHEMBL8404889 | 0.83 | HSD17B1 (0.49) | MEN1KMT2AMAPTLMNAKDM4E | |
| SCHEMBL1043301 | 0.83 | DYRK1A (0.61) | MEN1KMT2AMAPTLMNAKDM4E | |
| SCHEMBL8404893 | 0.81 | HSD17B1 (0.47) | MEN1KMT2AMAPTLMNASMN1; SMN2 | |
| SCHEMBL15349917 | 0.80 | DYRK1A (0.65) | MEN1KMT2AMAPTLMNAKDM4E | |
| SCHEMBL1040735 | 0.79 | DYRK1A (0.63) | MEN1KMT2AMAPTLMNAKDM4E | |
| SCHEMBL1038566 | 0.79 | TDP1 (0.62) | MEN1KMT2AMAPTLMNAKDM4E | |
| SCHEMBL1041605 | 0.76 | DYRK1A (0.57) | MEN1KMT2AMAPTLMNAKDM4E | |
| SCHEMBL2762212 | 0.75 | MEN1 (0.61) | MEN1KMT2AMAPTLMNAKDM4E | |
| SCHEMBL15349556 | 0.75 | DYRK1A (0.56) | MEN1KMT2AMAPTLMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5900426-A | ANTILIPEMIC AGENTS | NIPPON ZOKI PHARMACEUTICAL CO., LTD. (JP) | 1999-05-04 | — | — | US | disclosed |
| EP-0735029-B1 | Benzothiazole derivatives | NIPPON ZOKI PHARMACEUTICAL CO (JP) | 1998-06-03 | — | — | EP | disclosed |
| EP-0735029-A1 | Benzothiazole derivatives | NIPPON ZOKI PHARMACEUTICAL CO., LTD. (JP) | 1996-10-02 | — | — | EP | disclosed |