Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.33 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.33 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.33 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.32 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7021468 | 0.82 | HSD17B10 (0.45) | HSD17B10ADRB2ADRB1ADRB3POLB | |
| SCHEMBL7541159 | 0.78 | TSHR (0.39) | ADRB2ADRB3TDP1KDM4E | |
| SCHEMBL3837560 | 0.74 | CA1 (0.47) | TDP1KDM4EMAPT | |
| SCHEMBL10799380 | 0.72 | PPARG (0.40) | HSD17B10ADRB2ADRB1ADRB3POLB | |
| SCHEMBL1170181 | 0.71 | CA1 (0.45) | KDM4EMAPT | |
| SCHEMBL20958127 | 0.71 | CA1 (0.45) | KDM4EMAPT | |
| SCHEMBL16265139 | 0.71 | HSD17B10 (0.60) | HSD17B10ADRB2ADRB1TDP1KDM4E | |
| SCHEMBL22497668 | 0.71 | — | — | |
| SCHEMBL1071881 | 0.71 | — | — | |
| SCHEMBL13558573 | 0.71 | POLB (0.35) | HSD17B10POLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5994421-A | CROSSLINKING | SANYO CHEMICAL INDUSTRIES, LTD. (JP) | 1999-11-30 | — | — | US | disclosed |