Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARA | P10276 | 2/20 | 0.47 |
| ▸ | RARB | P10826 | 2/20 | 0.47 |
| ▸ | RARG | P13631 | 2/20 | 0.47 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.42 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | YWHAG | P61981 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
| ▸ | ABL1 | P00519 | 1/20 | 0.36 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7944862 | 0.89 | RARA (0.45) | RARARARBRARGPTGDRPTGDR2 | |
| SCHEMBL8400868 | 0.87 | YWHAG (0.47) | RARARARBRARGPTGDRPTGDR2 | |
| SCHEMBL7786595 | 0.83 | RARA (0.55) | RARARARBRARGPTGDRPTGDR2 | |
| SCHEMBL7940436 | 0.81 | RARA (0.55) | RARARARBRARGPTGDRPTGDR2 | |
| SCHEMBL8397569 | 0.81 | KMT2A (0.41) | RARARARBRARGPTGDRPTGDR2 | |
| SCHEMBL6566996 | 0.80 | RARA (0.48) | RARARARBRARGPTGDRPTGDR2 | |
| SCHEMBL8400745 | 0.80 | KMT2A (0.40) | RARARARBRARGPTGDRPTGDR2 | |
| SCHEMBL8397560 | 0.78 | KMT2A (0.39) | RARARARBRARGPTGDRPTGDR2 | |
| SCHEMBL6567017 | 0.78 | RARA (0.46) | RARARARBRARGPTGDRPTGDR2 | |
| SCHEMBL7933829 | 0.78 | GLA (0.38) | RARARARBRARGPTGDRPTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5914361-A | IMPART HEAT STABILITY TO ORGANIC MATERIALS, INCLUDING POLYOLEFINS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1999-06-22 | — | — | US | disclosed |