Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MLYCD | O95822 | 2/20 | 0.38 |
| ▸ | PLK1 | P53350 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | LTB4R2 | Q9NPC1 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | GALR3 | O60755 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8397881 | 0.91 | SMN1; SMN2 (0.49) | HPGDALDH1A1SMN1; SMN2LTB4R2HSD17B10 | |
| SCHEMBL8399138 | 0.88 | SMN1; SMN2 (0.41) | HPGDALDH1A1SMN1; SMN2LTB4R2HSD17B10 | |
| SCHEMBL8396482 | 0.86 | HTT (0.42) | ALDH1A1SMN1; SMN2LTB4R2HSD17B10KDM4E | |
| SCHEMBL8399279 | 0.83 | AR (0.39) | HPGDALDH1A1SMN1; SMN2HSD17B10KDM4E | |
| SCHEMBL8400320 | 0.82 | SMN1; SMN2 (0.46) | HPGDALDH1A1SMN1; SMN2HSD17B10NPC1 | |
| SCHEMBL8399081 | 0.81 | ALDH1A1 (0.47) | ALDH1A1SMN1; SMN2HSD17B10NPC1RAB9A | |
| SCHEMBL8399249 | 0.81 | HPGD (0.47) | HPGDALDH1A1SMN1; SMN2HSD17B10KDM4E | |
| SCHEMBL8395962 | 0.81 | MDM2 (0.43) | ALDH1A1SMN1; SMN2HSD17B10KDM4EKMT2A | |
| SCHEMBL8399145 | 0.81 | ATM (0.41) | HPGDALDH1A1MLYCDSMN1; SMN2LTB4R2 | |
| SCHEMBL8398027 | 0.81 | HTT (0.42) | ALDH1A1PLK1SMN1; SMN2HSD17B10RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0647636-B1 | BENZOTHIAZOLE COMPOUND, PROCESS FOR PRODUCING THE SAME, AND USE THEREOF | SENJU PHARMA CO (JP) | 1999-06-09 | — | — | EP | disclosed |
| US-5532257-A | ENZYME INHIBITOR | SENJU PHARMACEUTICAL CO., LTD (JP) | 1996-07-02 | — | — | US | disclosed |
| EP-0647636-A1 | BENZOTHIAZOLE COMPOUND, PROCESS FOR PRODUCING THE SAME, AND USE THEREOF | Senju Pharmaceutical Co., Ltd. (JP) | 1995-04-12 | — | — | EP | disclosed |