Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.59 |
| ▸ | MMP2 | P08253 | 4/20 | 0.53 |
| ▸ | ANPEP | P15144 | 3/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | PEPD | P12955 | 2/20 | 0.40 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.39 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | XPNPEP1 | Q9NQW7 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8401801 | 1.00 | ALDH1A1 (0.59) | ALDH1A1MMP2ANPEPTSHRATM | |
| SCHEMBL8401692 | 1.00 | ALDH1A1 (0.59) | ALDH1A1MMP2ANPEPTSHRATM | |
| SCHEMBL8401694 | 1.00 | ALDH1A1 (0.59) | ALDH1A1MMP2ANPEPTSHRATM | |
| SCHEMBL8401652 | 1.00 | ALDH1A1 (0.59) | ALDH1A1MMP2ANPEPTSHRATM | |
| SCHEMBL8401942 | 1.00 | ALDH1A1 (0.59) | ALDH1A1MMP2ANPEPTSHRATM | |
| SCHEMBL3272061 | 1.00 | ALDH1A1 (0.59) | ALDH1A1MMP2ANPEPTSHRATM | |
| SCHEMBL10251848 | 0.86 | ALDH1A1 (0.54) | ALDH1A1MMP2ANPEPATMMEN1 | |
| SCHEMBL8406472 | 0.86 | ALDH1A1 (0.54) | ALDH1A1MMP2ANPEPATMMEN1 | |
| SCHEMBL8406473 | 0.86 | ALDH1A1 (0.54) | ALDH1A1MMP2ANPEPATMMEN1 | |
| SCHEMBL9915286 | 0.86 | ALDH1A1 (0.54) | ALDH1A1MMP2ANPEPATMMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5928933-A | SEPARATING RACEMIC MIXTURE BY ENANTIOSELECTIVELY HYDROLYZING THE ESTER OF THE L-ISOMER; CHEMICAL INTERMEDIATE FOR 4-HYDROXYPROLINE | E. I. DU PONT DE NEMOURS & COMPANY (US) | 1999-07-27 | — | — | US | disclosed |