Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 17/20 | 0.51 |
| ▸ | ESR2 | Q92731 | 14/20 | 0.51 |
| ▸ | ACP1 | P24666 | 3/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8399903 | 0.95 | ACP1 (0.49) | ESR1ESR2ACP1 | |
| SCHEMBL8403332 | 0.94 | ESR1 (0.54) | ESR1ESR2ACP1 | |
| SCHEMBL8399991 | 0.93 | ACP1 (0.54) | ESR1ESR2ACP1 | |
| SCHEMBL8519431 | 0.93 | ESR1 (0.52) | ESR1ESR2 | |
| SCHEMBL8405723 | 0.92 | ACP1 (0.49) | ESR1ESR2ACP1 | |
| Hydrochloric Acid SCHEMBL8399940 | 0.92 | ACP1 (0.53) | ESR1ESR2ACP1 | |
| SCHEMBL8403143 | 0.90 | ACP1 (0.55) | ESR1ESR2ACP1 | |
| SCHEMBL8400253 | 0.90 | ESR1 (0.47) | ESR1ESR2 | |
| SCHEMBL8403321 | 0.88 | ESR1 (0.52) | ESR1ESR2ACP1 | |
| SCHEMBL8403805 | 0.88 | ESR1 (0.57) | ESR1ESR2ACP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5929090-A | NOVEL COMPOUNDS FOR TREATING ESTROGEN DEPRIVATION CAUSED BY MENOPAUSE OR OVARIECTOMY; TREATING OSTEOPOROSIS, CARDIOVASCULAR DISEASES, AND ENDOMETRIOSIS | ELI LILLY AND COMPANY (US) | 1999-07-27 | — | — | US | disclosed |