SCHEMBL8401759

SCHEMBL8401759

OC1CCCCCCC1(O)C1(c2ccccc2)CCCCCCC1c1ccccc1

nearest known ligand 0.38

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.37
KDM1A O60341 6/20 0.36
MAOA P21397 6/20 0.36
MAOB P27338 6/20 0.36
SLC18A3 Q16572 1/20 0.35
SLC6A4 P31645 1/20 0.35
SLC6A3 Q01959 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9508537 0.76 TSHR (0.41) TSHRKDM1AMAOAMAOBSLC18A3
SCHEMBL1535881 0.74 SLC6A9 (0.43) TSHRKDM1AMAOAMAOBSLC18A3
SCHEMBL11400432 0.73 CNR2 (0.41)
SCHEMBL31143852 0.73 KDM1A (0.43) KDM1AMAOAMAOB
SCHEMBL8323357 0.72 TSHR (0.45) TSHRKDM1AMAOAMAOBSLC18A3
SCHEMBL9295240 0.71 KDM1A (0.44) KDM1AMAOAMAOBSLC6A4SLC6A3
SCHEMBL7911980 0.71 CNR2 (0.42)
SCHEMBL6933056 0.71 CNR2 (0.42)
SCHEMBL6543483 0.71 CNR2 (0.42)
SCHEMBL1852711 0.71 CNR2 (0.42)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6008398-A Non-nucleotide phosphorus ester oligomers GENZYME CORPORATION (US) 1999-12-28 US disclosed
US-5919965-A Non-nucleotide phosphorus ester oligomers GENZYME CORPORATION (US) 1999-07-06 US disclosed
EP-0880532-A4 NON-NUCLEOTIDE PHOSPHOROUS ESTER OLIGOMERS PHARMAGENICS INC (US) 1999-06-09 EP disclosed
EP-0880532-A1 NON-NUCLEOTIDE PHOSPHOROUS ESTER OLIGOMERS PHARMAGENICS, INC. (US) 1998-12-02 EP disclosed
EP-0804443-A4 NON-NUCLEOTIDE PHOSPHORUS ESTER OLIGOMERS PHARMAGENICS INC (US) 1998-04-29 EP disclosed
EP-0804443-A1 NON-NUCLEOTIDE PHOSPHORUS ESTER OLIGOMERS PHARMAGENICS, INC. (US) 1997-11-05 EP disclosed
WO-1997028168-A1 NON-NUCLEOTIDE PHOSPHOROUS ESTER OLIGOMERS PHARMAGENICS, INC. (US) 1997-08-07 WO disclosed
WO-1996022297-A9 NON-NUCLEOTIDE PHOSPHORUS ESTER OLIGOMERS 1996-10-03 WO disclosed
WO-1996022297-A1 NON-NUCLEOTIDE PHOSPHORUS ESTER OLIGOMERS PHARMAGENICS, INC. (US) 1996-07-25 WO disclosed